HitPredict

Interactor 1: DRD3 (P35462)
D(3) dopamine receptor (Dopamine D3 receptor)
Gene: DRD3

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11384839
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 217
+	Hs
		686252 GASR_HUMAN (2-397): 1.03e-58: 199: 19.32		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		602194 DRD4_HUMAN (37-400): 6.26e-57: 193: 37.53		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		429008 ADRB2_HUMAN (1-399): 2.19e-56: 192: 23.33		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Dm
		993225 MOODY_DROME (13-400): 5.1e-57: 199: 18.43		GRAP_DROME (1-215): 5.1e-62: 194: 62.79
+	Hs
		522740 ADRB3_HUMAN (43-394): 2.61e-72: 233: 31.04		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		557623 GASR_HUMAN (2-397): 1.03e-58: 199: 19.32		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		337368 GASR_HUMAN (2-397): 1.03e-58: 199: 19.32		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46
+	Hs
		557605 DRD4_HUMAN (37-400): 6.26e-57: 193: 37.53		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		433596 5HT2A_HUMAN (5-400): 1.21e-61: 207: 25.48		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Hs
		412050 GASR_HUMAN (2-397): 1.03e-58: 199: 19.32		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		412089 5HT6R_HUMAN (6-400): 2.13e-57: 195: 25.12		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		428898 ADRB2_HUMAN (1-399): 2.19e-56: 192: 23.33		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Mm
		403428 5HT4R_MOUSE (324-400): 2.18e-13: 72.8: 41.56		SRC_MOUSE (161-215): 3.76e-11: 63.8: 31.58