HitPredict

Interactor 1: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1976 Hs			1 419
+	Hs
		724687 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		725095 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09
+	Hs
		725097 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYH11_HUMAN (13-392): 2.7e-09: 61.5: 13.42
+	Hs
		725092 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		724957 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		528386 MYH6_HUMAN (986-1976): 1.7e-60: 232: 17.60		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		725086 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MYO5A_HUMAN (38-342): 1.7e-24: 108: 14.65
+	Hs
		725065 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MYO5B_HUMAN (64-394): 2.99e-18: 89.7: 16.95
+	Hs
		724686 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		528435 MYH8_HUMAN (930-1976): 2.91e-65: 248: 17.93		MYH4_HUMAN (21-393): 8.88e-09: 60: 13.44
+	Hs
		724943 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89
+	Hs
		522657 MYH4_HUMAN (930-1976): 7.57e-64: 243: 17.51		MYH7_HUMAN (26-376): 1.58e-09: 62.3: 13.24
+	Hs
		528356 MYH6_HUMAN (986-1976): 1.7e-60: 232: 17.60		MYH6_HUMAN (4-395): 1.4e-09: 62.3: 11.48
+	Rn
		361106 MYH6_RAT (986-1976): 6.74e-61: 234: 17.98		MYH6_RAT (4-395): 9.94e-09: 59.6: 10.53
+	Mm
		93570 MYH9_MOUSE (963-1970): 1.32e-59: 230: 17.42		DESP_MOUSE (49-376): 9.41e-09: 60: 17.60
+	Hs
		724895 MYH14_HUMAN (889-1974): 4.36e-57: 221: 18.29		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		725189 MYH14_HUMAN (889-1974): 4.36e-57: 221: 18.29		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09