HitPredict

Interactor 1: FOXA2 (P35583)
Hepatocyte nuclear factor 3-beta (HNF-3-beta) (HNF-3B) (Forkhead box protein A2)
Gene: FOXA2

Interactor 2: HIF1A (Q61221)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein)
Gene: HIF1A

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 20609350
Identification Methods pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 10 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 459
Mm

1 836
+ Mm
+ Rn
+ Hs
+ Mm
+ Ce
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024