HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: PYGO1 (Q9Y3Y4)
Pygopus homolog 1
Gene: PYGO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 419
+	Hs
		725311 TLX1_HUMAN (1-330): 5.03e-61: 199: 100.00		PYGO2_HUMAN (2-419): 4.2e-47: 168: 32.38
+	Hs
		725330 TLX1_HUMAN (1-330): 5.03e-61: 199: 100.00		CHD7_HUMAN (20-302): 2.76e-38: 149: 10.71
+	Hs
		226592 TLX2_HUMAN (4-327): 1.06e-41: 148: 51.79		PYGO2_HUMAN (2-419): 4.2e-47: 168: 32.38
+	Hs
		725285 TLX1_HUMAN (1-330): 5.03e-61: 199: 100.00		KMT2C_HUMAN (38-338): 3.66e-25: 110: 11.68
+	Hs
		226614 TLX2_HUMAN (4-327): 1.06e-41: 148: 51.79		CHD7_HUMAN (20-302): 2.76e-38: 149: 10.71
+	Hs
		225094 TLX3_HUMAN (11-325): 3.91e-31: 120: 48.25		PYGO2_HUMAN (2-419): 4.2e-47: 168: 32.38
+	Hs
		1033801 PO5F1_HUMAN (31-327): 1.03e-30: 120: 17.00		CHD7_HUMAN (20-302): 2.76e-38: 149: 10.71
+	Hs
		225131 TLX3_HUMAN (11-325): 3.91e-31: 120: 48.25		CHD7_HUMAN (20-302): 2.76e-38: 149: 10.71
+	Hs
		226574 TLX2_HUMAN (4-327): 1.06e-41: 148: 51.79		KMT2C_HUMAN (38-338): 3.66e-25: 110: 11.68
+	Hs
		225064 TLX3_HUMAN (11-325): 3.91e-31: 120: 48.25		KMT2C_HUMAN (38-338): 3.66e-25: 110: 11.68
+	Mm
		629428 PO5F1_MOUSE (32-327): 7.6e-31: 121: 15.15		ANR17_MOUSE (3-354): 6.15e-24: 107: 15.55
+	Hs
		942450 GSC_HUMAN (19-285): 1.33e-30: 118: 20.97		KMT2C_HUMAN (38-338): 3.66e-25: 110: 11.68
+	Mm
		629255 PO5F1_MOUSE (32-327): 7.6e-31: 121: 15.15		SMCA4_MOUSE (21-312): 1.3e-20: 96.6: 12.16
+	Hs
		214484 HXA2_HUMAN (92-275): 1.68e-34: 131: 19.51		SYNJ1_HUMAN (107-352): 4.72e-09: 60.8: 9.73
+	Mm
		629359 PO5F1_MOUSE (32-327): 7.6e-31: 121: 15.15		KMT2C_MOUSE (8-354): 8.01e-09: 60: 10.99