HitPredict

Interactor 1: B1AHC3 (B1AHC3)
PRR5-ARHGAP8 readthrough
Gene: PRR5-ARHGAP8

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RhoGAP~SH3_1
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 564 Hs			1 347
+	Hs
		72897 B1AHC3_HUMAN (1-564): 0: 644: 100.00		SH3G2_HUMAN (1-347): 1.33e-86: 266: 65.91
+	Hs
		72896 B1AHC3_HUMAN (1-564): 0: 644: 100.00		SH3G1_HUMAN (1-347): 3.07e-80: 251: 66.03
+	Hs
		85494 B7ZMA4_HUMAN (96-564): 6.26e-164: 477: 96.09		SH3G3_HUMAN (1-347): 6.72e-91: 277: 100.00
+	Hs
		85493 B7ZMA4_HUMAN (96-564): 6.26e-164: 477: 96.09		SH3G2_HUMAN (1-347): 1.33e-86: 266: 65.91
+	Hs
		85492 B7ZMA4_HUMAN (96-564): 6.26e-164: 477: 96.09		SH3G1_HUMAN (1-347): 3.07e-80: 251: 66.03
+	Hs
		1017538 RHG08_HUMAN (132-564): 3.76e-149: 438: 93.32		SH3G3_HUMAN (1-347): 6.72e-91: 277: 100.00
+	Hs
		72892 B1AHC3_HUMAN (1-564): 0: 644: 100.00		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		1017537 RHG08_HUMAN (132-564): 3.76e-149: 438: 93.32		SH3G2_HUMAN (1-347): 1.33e-86: 266: 65.91
+	Hs
		1316653 Q8IZM6_HUMAN (132-564): 1.07e-154: 451: 99.77		SH3G1_HUMAN (1-347): 3.07e-80: 251: 66.03
+	Hs
		1017536 RHG08_HUMAN (132-564): 3.76e-149: 438: 93.32		SH3G1_HUMAN (1-347): 3.07e-80: 251: 66.03
+	Hs
		1061284 RHG01_HUMAN (98-519): 3.66e-131: 391: 50.92		SH3G1_HUMAN (1-347): 3.07e-80: 251: 66.03
+	Hs
		85487 B7ZMA4_HUMAN (96-564): 6.26e-164: 477: 96.09		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		212786 SRGP3_HUMAN (270-561): 9.8e-67: 236: 23.64		SH3G2_HUMAN (1-347): 1.33e-86: 266: 65.91
+	Hs
		212785 SRGP3_HUMAN (270-561): 9.8e-67: 236: 23.64		SH3G1_HUMAN (1-347): 3.07e-80: 251: 66.03
+	Hs
		1124647 RHG24_HUMAN (276-564): 5.19e-69: 238: 22.70		SRC8_HUMAN (7-343): 2.87e-51: 180: 14.49
+	Hs
		1165242 RHG44_HUMAN (263-560): 6.68e-66: 231: 24.59		3BP1_HUMAN (6-252): 2.24e-38: 146: 17.63
+	Hs
		1165233 RHG44_HUMAN (263-560): 6.68e-66: 231: 24.59		RHG17_HUMAN (6-251): 8.97e-35: 137: 20.83
+	Hs
		212764 SRGP3_HUMAN (270-561): 9.8e-67: 236: 23.64		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		987756 RHG12_HUMAN (278-512): 2.48e-66: 233: 23.53		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38
+	Hs
		67649 RHG32_HUMAN (305-549): 9.52e-64: 229: 21.81		GRB2_HUMAN (290-346): 9.97e-12: 65.5: 41.38