HitPredict

Interactor 1: B7ZMA4 (B7ZMA4)
LOC553158 protein
Gene: LOC553158

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RhoGAP~SH3_1
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 486 Hs			1 217
+	Hs
		72892 B1AHC3_HUMAN (1-486): 9.38e-168: 486: 95.27		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		987971 RHG35_HUMAN (144-461): 4.42e-66: 233: 20.12		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		212764 SRGP3_HUMAN (175-484): 2.17e-64: 227: 22.12		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		987675 Q1RLN5_HUMAN (183-435): 1.91e-64: 224: 21.88		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		987756 RHG12_HUMAN (183-435): 3.59e-64: 224: 21.88		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		557256 RHG01_HUMAN (44-440): 6.19e-120: 360: 54.02		SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58
+	Hs
		440109 RHG21_HUMAN (154-485): 2.12e-71: 248: 19.76		LCK_HUMAN (3-202): 7.98e-34: 128: 28.44
+	Hs
		440117 RHG17_HUMAN (198-483): 3.64e-63: 222: 22.41		LCK_HUMAN (3-202): 7.98e-34: 128: 28.44
+	Hs
		593948 CHIO_HUMAN (13-434): 5.79e-78: 253: 15.50		NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14
+	Hs
		586972 CHIN_HUMAN (13-434): 2.04e-77: 251: 15.84		NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14
+	Hs
		594020 RHG21_HUMAN (154-485): 2.12e-71: 248: 19.76		NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14
+	Hs
		362308 RHG17_HUMAN (198-483): 3.64e-63: 222: 22.41		ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46
+	Hs
		463571 RHG21_HUMAN (154-485): 2.12e-71: 248: 19.76		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47
+	Hs
		156400 RHG33_HUMAN (206-485): 1.25e-66: 234: 24.01		FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58
+	Hs
		440649 PRUN2_HUMAN (31-210): 5.85e-64: 227: 32.07		FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58
+	Mm
		813524 RHG33_MOUSE (207-485): 1.35e-63: 225: 24.09		FYN_MOUSE (161-215): 9.17e-13: 68.5: 31.58
+	Hs
		463177 PRUN2_HUMAN (31-210): 5.85e-64: 227: 32.07		YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33
+	Hs
		557402 PRUN2_HUMAN (31-210): 5.85e-64: 227: 32.07		SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58
+	Hs
		463674 PRUN2_HUMAN (31-210): 5.85e-64: 227: 32.07		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47
+	Hs
		463636 RHG12_HUMAN (183-435): 3.59e-64: 224: 21.88		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47