HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 759
+	Mm
		972322 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		GIT2_MOUSE (1-759): 2.22e-151: 459: 86.17
+	Mm
		972246 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		GIT1_MOUSE (1-758): 2.14e-138: 428: 63.30
+	Hs
		972134 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		AGAP1_HUMAN (3-224): 2.72e-59: 217: 33.33
+	Hs
		95979 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		E7EUN2_HUMAN (3-224): 5.53e-57: 212: 33.33
+	Hs
		971895 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		AGAP3_HUMAN (3-224): 1.49e-56: 209: 35.11
+	Hs
		730158 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		AGAP3_HUMAN (3-224): 1.49e-56: 209: 35.11
+	Hs
		171218 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MYPT1_HUMAN (94-670): 3.89e-54: 204: 10.75
+	Hs
		171181 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		MYPT1_HUMAN (94-670): 3.89e-54: 204: 10.75
+	Hs
		62926 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		POTEF_HUMAN (93-665): 1.12e-53: 203: 13.04
+	Hs
		62910 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		POTEF_HUMAN (93-665): 1.12e-53: 203: 13.04
+	Hs
		730182 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		AGAP2_HUMAN (3-224): 1.3e-53: 203: 32.00
+	Hs
		971834 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ARAP2_HUMAN (7-186): 2.95e-51: 196: 32.24
+	Hs
		730103 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		ARAP2_HUMAN (7-186): 2.95e-51: 196: 32.24
+	Hs
		971417 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ANK2_HUMAN (61-417): 4.25e-44: 174: 12.85
+	Hs
		274129 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ANR17_HUMAN (41-254): 5.41e-28: 123: 16.28
+	Hs
		274105 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		ANR17_HUMAN (41-254): 5.41e-28: 123: 16.28
+	Hs
		971756 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ANKH1_HUMAN (41-254): 2.9e-27: 121: 16.28
+	Hs
		971545 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ACAP2_HUMAN (97-292): 1.91e-23: 108: 17.68
+	Hs
		972076 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		RAI14_HUMAN (120-504): 2.88e-16: 85.4: 16.58
+	Hs
		730300 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		RAI14_HUMAN (120-504): 2.88e-16: 85.4: 16.58