HitPredict

Interactor 1: SCN2A (B1AWN6)
Sodium channel protein type 2 subunit alpha (Voltage-gated sodium channel subunit alpha Nav1.2)
Gene: SCN2A

Interactor 2: HECD3 (Q3U487)
E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3)
Gene: Hectd3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	38514708
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2006 Mm			1 861
+	Mm
		73088 SCN2A_MOUSE (1-2006): 0: 2119: 100.00		NEDD4_MOUSE (373-853): 2.4e-172: 523: 20.08
+	Mm
		73078 SCN2A_MOUSE (1-2006): 0: 2119: 100.00		E9PXB7_MOUSE (379-853): 1.18e-170: 517: 18.89
+	Hs
		771756 SCN1A_HUMAN (1-1999): 0: 1985: 85.45		SMUF2_HUMAN (337-855): 0: 540: 20.35
+	Hs
		771743 SCN1A_HUMAN (1-1999): 0: 1985: 85.45		NEDD4_HUMAN (347-853): 7.25e-171: 531: 18.85
+	Hs
		1155140 SCN9A_HUMAN (4-2006): 0: 1965: 76.22		SMUF2_HUMAN (337-855): 0: 540: 20.35
+	Mm
		861880 SCN9A_MOUSE (4-2003): 0: 1939: 76.12		NEDD4_MOUSE (373-853): 2.4e-172: 523: 20.08
+	Mm
		97741 SCN9A_MOUSE (4-2003): 0: 1939: 76.12		E9PXB7_MOUSE (379-853): 1.18e-170: 517: 18.89
+	Mm
		861904 SCN8A_MOUSE (1-2005): 0: 1869: 73.30		NEDD4_MOUSE (373-853): 2.4e-172: 523: 20.08
+	Hs
		861842 SCN8A_HUMAN (1-2005): 0: 1859: 73.54		NEDD4_HUMAN (347-853): 7.25e-171: 531: 18.85
+	Mm
		97754 SCN8A_MOUSE (1-2005): 0: 1869: 73.30		E9PXB7_MOUSE (379-853): 1.18e-170: 517: 18.89
+	Hs
		1127640 SCN5A_HUMAN (3-1999): 0: 1804: 61.66		SMUF2_HUMAN (337-855): 0: 540: 20.35
+	Hs
		861611 SCN5A_HUMAN (3-1999): 0: 1804: 61.66		NEDD4_HUMAN (347-853): 7.25e-171: 531: 18.85
+	Hs
		1127634 SCN5A_HUMAN (3-1999): 0: 1804: 61.66		NED4L_HUMAN (379-853): 1.83e-169: 518: 18.89
+	Mm
		861901 SCN5A_MOUSE (3-1999): 0: 1799: 61.63		NEDD4_MOUSE (373-853): 2.4e-172: 523: 20.08
+	Hs
		132037 SCN5A_HUMAN (3-1999): 0: 1804: 61.66		WWP2_HUMAN (354-855): 6.29e-169: 514: 18.85
+	Mm
		97752 SCN5A_MOUSE (3-1999): 0: 1799: 61.63		E9PXB7_MOUSE (379-853): 1.18e-170: 517: 18.89
+	Mm
		861885 SCNAA_MOUSE (8-2002): 0: 1742: 54.04		NEDD4_MOUSE (373-853): 2.4e-172: 523: 20.08
+	Mm
		97743 SCNAA_MOUSE (8-2002): 0: 1742: 54.04		E9PXB7_MOUSE (379-853): 1.18e-170: 517: 18.89
+	Hs
		861860 SCNAA_HUMAN (8-2005): 0: 1707: 54.37		NEDD4_HUMAN (347-853): 7.25e-171: 531: 18.85
+	Mm
		97737 Q3UF73_MOUSE (1-202): 4.81e-111: 353: 85.64		E9PXB7_MOUSE (379-853): 1.18e-170: 517: 18.89