HitPredict

Interactor 1: CEAM8 (P31997)
Cell adhesion molecule CEACAM8 (CD67 antigen) (Carcinoembryonic antigen CGM6) (Carcinoembryonic antigen-related cell adhesion molecule 8) (CEA cell adhesion molecule 8) (Non-specific cross-reacting antigen NCA-95) (CD antigen CD66b)
Gene: CEACAM8

Interactor 2: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Calx-beta~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 349 Hs			1 4008
+	Hs
		1294397 PSG8_HUMAN (32-326): 1.22e-45: 162: 40.88		FRAS1_HUMAN (1-4008): 0: 2793: 100.00
+	Hs
		731856 CEAM8_HUMAN (1-349): 8.25e-87: 267: 100.00		FREM2_HUMAN (1229-3238): 1.69e-107: 390: 18.67
+	Hs
		501764 CEAM6_HUMAN (1-349): 1.14e-88: 271: 76.79		FREM3_HUMAN (1350-3238): 2.36e-93: 342: 16.82
+	Hs
		1211502 PSG8_HUMAN (32-326): 1.22e-45: 162: 40.88		FREM2_HUMAN (1229-3238): 1.69e-107: 390: 18.67
+	Hs
		644579 CEAM6_HUMAN (1-349): 1.14e-88: 271: 76.79		TENX_HUMAN (709-1137): 1.18e-47: 192: 13.30
+	Hs
		1047673 PXDN_HUMAN (121-349): 1.9e-47: 174: 19.75		NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46
+	Hs
		731885 CEAM8_HUMAN (1-349): 8.25e-87: 267: 100.00		AGRV1_HUMAN (2798-3348): 1.46e-17: 93.6: 15.69
+	Hs
		731887 CEAM8_HUMAN (1-349): 8.25e-87: 267: 100.00		PCSK5_HUMAN (12-434): 3.79e-14: 82: 13.91
+	Hs
		731845 CEAM8_HUMAN (1-349): 8.25e-87: 267: 100.00		FAT1_HUMAN (213-422): 1.32e-09: 67: 10.43
+	Hs
		731865 CEAM8_HUMAN (1-349): 8.25e-87: 267: 100.00		FAT4_HUMAN (332-510): 2.21e-09: 66.2: 12.57
+	Hs
		731901 CEAM8_HUMAN (1-349): 8.25e-87: 267: 100.00		CELR3_HUMAN (182-386): 2.12e-09: 66.2: 13.40
+	Hs
		1360647 PSG8_HUMAN (32-326): 1.22e-45: 162: 40.88		AGRV1_HUMAN (2798-3348): 1.46e-17: 93.6: 15.69
+	Hs
		1366065 PXDN_HUMAN (121-349): 1.9e-47: 174: 19.75		NELL2_HUMAN (23-499): 1.93e-09: 66.2: 22.65
+	Hs
		1366058 PXDN_HUMAN (121-349): 1.9e-47: 174: 19.75		NELL1_HUMAN (157-646): 2.8e-09: 65.5: 22.39
+	Hs
		1439459 PSG8_HUMAN (32-326): 1.22e-45: 162: 40.88		CELR2_HUMAN (4-196): 8.58e-10: 67.8: 12.09
+	Hs
		1127613 PSG8_HUMAN (32-326): 1.22e-45: 162: 40.88		FAT1_HUMAN (213-422): 1.32e-09: 67: 10.43
+	Hs
		1250370 PSG8_HUMAN (32-326): 1.22e-45: 162: 40.88		FAT4_HUMAN (332-510): 2.21e-09: 66.2: 12.57
+	Hs
		1452771 PSG8_HUMAN (32-326): 1.22e-45: 162: 40.88		CELR3_HUMAN (182-386): 2.12e-09: 66.2: 13.40
+	Hs
		543440 PSG1_HUMAN (32-319): 1.27e-44: 160: 41.18		CELR3_HUMAN (182-386): 2.12e-09: 66.2: 13.40
+	Hs
		543432 PSG1_HUMAN (32-319): 1.27e-44: 160: 41.18		FAT3_HUMAN (122-226): 7.97e-09: 64.7: 14.41