HitPredict

Interactor 1: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Interactor 2: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20724660
Identification Methods	enzymatic study
Interaction Type	ubiquitination reaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 574 Hs			1 145
+	Hs
		734819 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27
+	Hs
		734563 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82
+	Hs
		734581 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06
+	Hs
		734570 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D3_HUMAN (10-144): 9.91e-58: 178: 22.06
+	Hs
		734733 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2E2_HUMAN (2-143): 7.87e-57: 177: 23.08
+	Hs
		734564 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2E1_HUMAN (1-143): 2.16e-56: 176: 22.92
+	Hs
		734587 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Hs
		895769 ARF6_HUMAN (399-567): 3.05e-87: 269: 54.44		UB2D3_HUMAN (10-144): 9.91e-58: 178: 22.06
+	Hs
		1356055 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27
+	Hs
		1151762 Q6GX22_HUMAN (23-400): 6.72e-69: 237: 19.60		UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27
+	Hs
		849480 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82
+	Hs
		919896 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06
+	Hs
		1282363 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2E3_HUMAN (2-143): 6.26e-57: 178: 23.08
+	Hs
		895945 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D3_HUMAN (10-144): 9.91e-58: 178: 22.06
+	Hs
		1297378 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2E2_HUMAN (2-143): 7.87e-57: 177: 23.08
+	Hs
		851905 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2E1_HUMAN (1-143): 2.16e-56: 176: 22.92
+	Zm
		74077 B4FB55_MAIZE (401-568): 1.95e-60: 201: 15.61		B6T659_MAIZE (39-130): 5.46e-14: 66.5: 29.03