HitPredict

Interactor 1: RAN2 (P41917)
GTP-binding nuclear protein Ran-2 (Ras-related nuclear protein 2)
Gene: RAN2

Interactor 2: IMB1 (Q9FJD4)
Importin subunit beta-1 (Karyopherin subunit beta-1) (ATKPNB1)
Gene: KPNB1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	23582042
Identification Methods	two hybrid, protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IBN_N~Ras
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006606 - protein import into nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 221 At			1 870
+	At
		1300601 RAN3_ARATH (1-221): 4.06e-80: 240: 96.38		IMB1_ARATH (1-870): 0: 601: 100.00
+	At
		836671 RAN1_ARATH (1-221): 1.32e-78: 236: 96.38		IMB1_ARATH (1-870): 0: 601: 100.00
+	Hs
		981493 RAN_HUMAN (1-218): 6.39e-76: 229: 74.77		IMB1_HUMAN (3-867): 3.9e-165: 504: 37.95
+	Sc
		745880 GSP1_YEAST (1-217): 1.49e-77: 233: 75.58		IMB1_YEAST (2-870): 6.94e-130: 412: 30.87
+	Sc
		734639 GSP2_YEAST (1-220): 8.73e-79: 237: 74.55		IMB3_YEAST (5-824): 1.7e-111: 368: 15.23
+	Sc
		734638 GSP1_YEAST (1-217): 1.49e-77: 233: 75.58		IMB3_YEAST (5-824): 1.7e-111: 368: 15.23
+	At
		836667 RAN1_ARATH (1-221): 1.32e-78: 236: 96.38		TNPO1_ARATH (3-869): 4.54e-112: 365: 17.51
+	Hs
		251207 RB11A_HUMAN (1-212): 7.53e-76: 229: 25.58		RNBP6_HUMAN (2-852): 3.95e-99: 335: 15.48
+	Hs
		934050 RAN_HUMAN (1-218): 6.39e-76: 229: 74.77		XPO2_HUMAN (3-851): 5.51e-98: 329: 11.77
+	Hs
		334737 RAN_HUMAN (1-218): 6.39e-76: 229: 74.77		IPO7_HUMAN (5-850): 2.61e-95: 323: 11.43
+	Hs
		134001 RAN_HUMAN (1-218): 6.39e-76: 229: 74.77		IPO5_HUMAN (2-851): 9.46e-92: 315: 14.21
+	Sc
		745938 GSP2_YEAST (1-220): 8.73e-79: 237: 74.55		IMB2_YEAST (3-718): 9.09e-41: 164: 16.23
+	Sc
		745716 GSP1_YEAST (1-217): 1.49e-77: 233: 75.58		IMB2_YEAST (3-718): 9.09e-41: 164: 16.23
+	Dm
		1485211 RANL_DROME (14-213): 7.65e-86: 254: 59.00		Q9VRV8_DROME (171-869): 1.55e-23: 109: 12.86
+	Hs
		981621 RAN_HUMAN (1-218): 6.39e-76: 229: 74.77		TNPO1_HUMAN (102-870): 1.14e-27: 122: 11.66
+	Hs
		164559 RAN_HUMAN (1-218): 6.39e-76: 229: 74.77		TNPO2_HUMAN (104-869): 9.76e-24: 109: 11.35
+	Dm
		197105 O18332_DROME (1-201): 8.07e-79: 236: 25.98		Q9VN44_DROME (95-794): 1.66e-14: 80.3: 13.51
+	Hs
		981730 RAN_HUMAN (1-218): 6.39e-76: 229: 74.77		IPO11_HUMAN (5-140): 2.58e-09: 63.2: 34.56