HitPredict

Interactor 1: PP4C (P32345)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (EC 3.1.3.16) (Phosphatase PP2A-like catalytic subunit PPH3)
Gene: PPH3

Interactor 2: TAP42 (Q04372)
Type 2A phosphatase-associated protein 42
Gene: TAP42

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	14551259, 15447631
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Metallophos~TAP42
Common GO terms	GO:1903432 - regulation of TORC1 signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 308 Sc			1 366
+	At
		873846 PPX1_ARATH (1-308): 0: 516: 64.08		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	At
		1058785 PP2A3_ARATH (2-308): 0: 515: 54.07		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	Hs
		951961 PP4C_HUMAN (1-308): 0: 524: 62.66		IGBP1_HUMAN (18-366): 1.56e-88: 271: 22.38
+	At
		874361 PP2A4_ARATH (2-308): 0: 513: 53.75		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	At
		1058776 PP2A2_ARATH (3-308): 0: 511: 53.27		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	Mm
		977633 PP2AB_MOUSE (3-308): 0: 518: 52.29		IGBP1_MOUSE (18-366): 3.9e-89: 273: 21.27
+	Mm
		994005 PP2AA_MOUSE (3-308): 0: 518: 52.29		IGBP1_MOUSE (18-366): 3.9e-89: 273: 21.27
+	At
		147070 PP2A5_ARATH (3-308): 0: 508: 52.29		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	Dm
		661973 PP2A_DROME (3-308): 0: 515: 51.96		Q9VJZ5_DROME (18-365): 5.75e-89: 274: 21.16
+	Hs
		977458 PP2AB_HUMAN (3-308): 0: 518: 52.29		IGBP1_HUMAN (18-366): 1.56e-88: 271: 22.38
+	Hs
		994174 PP2AA_HUMAN (3-308): 0: 518: 52.29		IGBP1_HUMAN (18-366): 1.56e-88: 271: 22.38
+	At
		1058780 PP2A1_ARATH (3-308): 0: 507: 53.27		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	Dm
		304791 PP4C_DROME (3-308): 0: 514: 61.77		Q9VJZ5_DROME (18-365): 5.75e-89: 274: 21.16
+	Sc
		633509 PP11_YEAST (5-286): 2.25e-130: 375: 58.10		TAP42_YEAST (1-366): 7.02e-137: 396: 100.00
+	Ce
		113999 PP2A_CAEEL (1-308): 0: 520: 53.25		PP4RS_CAEEL (26-366): 2.36e-80: 250: 23.63
+	Ce
		1445010 PP4C1_CAEEL (3-308): 0: 517: 62.87		PP4RS_CAEEL (26-366): 2.36e-80: 250: 23.63
+	At
		1319924 FYPP1_ARATH (2-292): 1.41e-138: 395: 59.25		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	At
		1319915 FYPP3_ARATH (2-292): 5.35e-138: 394: 59.25		TAP46_ARATH (29-362): 1.4e-91: 281: 17.36
+	Hs
		143619 PPP6_HUMAN (2-308): 1.96e-138: 395: 59.28		IGBP1_HUMAN (18-366): 1.56e-88: 271: 22.38
+	Dm
		1176862 PPP6_DROME (1-308): 1.49e-133: 382: 58.12		Q9VJZ5_DROME (18-365): 5.75e-89: 274: 21.16