HitPredict

Interactor 1: MYO9A (B2RTY4)
Unconventional myosin-IXa (Unconventional myosin-9a)
Gene: MYO9A

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, RA~Ras, Ras~RhoGAP
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2548 Hs			1 236
+	Hs
		74012 MYO9A_HUMAN (1-2548): 0: 1620: 100.00		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		74011 MYO9A_HUMAN (1-2548): 0: 1620: 100.00		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Hs
		988821 MYO5B_HUMAN (93-1595): 0: 895: 20.04		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		1271051 MYO6_HUMAN (142-688): 7.03e-109: 382: 38.57		RHOU_HUMAN (32-236): 2.91e-89: 265: 60.48
+	Hs
		1396657 MYO6_HUMAN (142-688): 7.03e-109: 382: 38.57		RHOV_HUMAN (1-236): 1.28e-77: 235: 100.00
+	Hs
		988824 MYO6_HUMAN (142-688): 7.03e-109: 382: 38.57		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		581373 MYO6_HUMAN (142-688): 7.03e-109: 382: 38.57		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		962630 MYO6_HUMAN (142-688): 7.03e-109: 382: 38.57		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		955752 MYO6_HUMAN (142-688): 7.03e-109: 382: 38.57		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Hs
		962018 MYO9B_HUMAN (1182-2470): 9.21e-86: 316: 21.41		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		772724 MYH9_HUMAN (815-1535): 1.6e-82: 305: 17.81		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		772743 MYH9_HUMAN (815-1535): 1.6e-82: 305: 17.81		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		955132 MYO9B_HUMAN (1182-2470): 9.21e-86: 316: 21.41		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Ce
		98435 F0IWT2_CAEEL (860-1120): 2.05e-56: 220: 33.97		CDC42_CAEEL (32-215): 8.6e-67: 206: 54.89
+	Hs
		953688 MYO10_HUMAN (816-1063): 1.07e-28: 129: 28.99		RAC3_HUMAN (32-206): 8.74e-75: 226: 56.00
+	Hs
		1271065 MYO5A_HUMAN (1373-1955): 3.17e-13: 78.1: 7.22		RHOU_HUMAN (32-236): 2.91e-89: 265: 60.48
+	Hs
		1396666 MYO5A_HUMAN (1373-1955): 3.17e-13: 78.1: 7.22		RHOV_HUMAN (1-236): 1.28e-77: 235: 100.00
+	Hs
		601517 MYO5A_HUMAN (1373-1955): 3.17e-13: 78.1: 7.22		RHOQ_HUMAN (23-236): 1.98e-75: 228: 50.00