HitPredict

Interactor 1: GSP1 (P32835)
GTP-binding nuclear protein GSP1/CNR1 (Chromosome stability protein 17) (GTPase Ran homolog) (Genetic suppressor of PRP20-1)
Gene: GSP1

Interactor 2: SXM1 (Q04175)
Importin beta SMX1 (Suppressor of mRNA export mutant protein 1) (karyopherin-108)
Gene: SXM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21329658
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cse1~Ras, IBN_N~Ras
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Sc			1 944
+	Hs
		334737 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IPO7_HUMAN (2-943): 0: 625: 21.17
+	Hs
		189141 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IPO8_HUMAN (2-943): 0: 597: 20.00
+	Hs
		934050 RAN_HUMAN (1-216): 5e-77: 232: 80.56		XPO2_HUMAN (3-942): 2.25e-163: 505: 15.42
+	Dm
		1485211 RANL_DROME (13-219): 2.11e-90: 266: 59.42		Q9VRV8_DROME (4-837): 2.78e-144: 453: 11.01
+	Hs
		981621 RAN_HUMAN (1-216): 5e-77: 232: 80.56		TNPO1_HUMAN (12-837): 1.9e-146: 458: 11.17
+	At
		836667 RAN1_ARATH (1-216): 9.55e-94: 275: 75.58		TNPO1_ARATH (4-835): 3.9e-127: 408: 12.72
+	Hs
		134001 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IPO5_HUMAN (3-924): 9.17e-140: 447: 10.11
+	At
		836671 RAN1_ARATH (1-216): 9.55e-94: 275: 75.58		IMB1_ARATH (6-769): 1.88e-124: 400: 12.84
+	Hs
		164559 RAN_HUMAN (1-216): 5e-77: 232: 80.56		TNPO2_HUMAN (12-837): 1.4e-137: 435: 10.50
+	Sc
		745796 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		NMD5_YEAST (2-940): 1.54e-135: 434: 23.44
+	At
		836678 RAN2_ARATH (1-216): 2.35e-88: 261: 75.58		IMB1_ARATH (6-769): 1.88e-124: 400: 12.84
+	At
		1300601 RAN3_ARATH (1-219): 1.47e-82: 246: 74.55		IMB1_ARATH (6-769): 1.88e-124: 400: 12.84
+	Sp
		150708 SPI1_SCHPO (5-219): 7.81e-78: 234: 88.37		CSE1_SCHPO (5-941): 3.88e-124: 401: 16.32
+	Sc
		745934 GSP2_YEAST (1-219): 1.92e-78: 236: 96.82		CSE1_YEAST (1-938): 1.22e-116: 381: 16.30
+	Sc
		745951 GSP2_YEAST (1-219): 1.92e-78: 236: 96.82		KA120_YEAST (2-814): 2.48e-115: 379: 16.49
+	Sc
		745684 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		CSE1_YEAST (1-938): 1.22e-116: 381: 16.30
+	Hs
		981493 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IMB1_HUMAN (6-774): 7.43e-117: 380: 11.65
+	Sc
		745852 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		KA120_YEAST (2-814): 2.48e-115: 379: 16.49
+	Hs
		981648 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IPO9_HUMAN (4-830): 6.07e-111: 368: 12.90
+	Sc
		745813 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		IMB5_YEAST (7-898): 5.44e-22: 104: 12.49