HitPredict

Interactor 1: GSP1 (P32835)
GTP-binding nuclear protein GSP1/CNR1 (Chromosome stability protein 17) (GTPase Ran homolog) (Genetic suppressor of PRP20-1)
Gene: GSP1

Interactor 2: NMD5 (P46970)
Nonsense-mediated mRNA decay protein 5 (Karyopherin-119)
Gene: NMD5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	15679097, 15864302, 21329658
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IBN_N~Ras
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Sc			1 1048
+	Hs
		334737 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IPO7_HUMAN (1-1045): 0: 603: 22.31
+	Hs
		189141 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IPO8_HUMAN (1-1045): 0: 600: 22.51
+	Dm
		1485211 RANL_DROME (13-219): 2.11e-90: 266: 59.42		Q9VRV8_DROME (3-944): 2.84e-151: 474: 9.98
+	Hs
		981621 RAN_HUMAN (1-216): 5e-77: 232: 80.56		TNPO1_HUMAN (11-944): 4.57e-152: 476: 9.60
+	Hs
		934050 RAN_HUMAN (1-216): 5e-77: 232: 80.56		XPO2_HUMAN (2-973): 1.19e-149: 472: 14.66
+	Hs
		164559 RAN_HUMAN (1-216): 5e-77: 232: 80.56		TNPO2_HUMAN (11-944): 1.77e-143: 454: 10.42
+	At
		836667 RAN1_ARATH (1-216): 9.55e-94: 275: 75.58		TNPO1_ARATH (3-940): 1.23e-121: 396: 12.02
+	At
		836671 RAN1_ARATH (1-216): 9.55e-94: 275: 75.58		IMB1_ARATH (5-935): 3.87e-116: 380: 10.92
+	At
		836678 RAN2_ARATH (1-216): 2.35e-88: 261: 75.58		IMB1_ARATH (5-935): 3.87e-116: 380: 10.92
+	Sc
		745934 GSP2_YEAST (1-219): 1.92e-78: 236: 96.82		CSE1_YEAST (2-973): 5.72e-123: 401: 14.51
+	Sc
		745684 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		CSE1_YEAST (2-973): 5.72e-123: 401: 14.51
+	Sc
		745951 GSP2_YEAST (1-219): 1.92e-78: 236: 96.82		KA120_YEAST (1-940): 2.04e-118: 391: 14.06
+	At
		1300601 RAN3_ARATH (1-219): 1.47e-82: 246: 74.55		IMB1_ARATH (5-935): 3.87e-116: 380: 10.92
+	Hs
		981648 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IPO9_HUMAN (4-1045): 6.37e-119: 392: 14.35
+	Sc
		745852 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		KA120_YEAST (1-940): 2.04e-118: 391: 14.06
+	Sc
		745865 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		SXM1_YEAST (4-1047): 7.83e-115: 379: 24.41
+	Hs
		981493 RAN_HUMAN (1-216): 5e-77: 232: 80.56		IMB1_HUMAN (5-930): 9.51e-111: 366: 10.60
+	Sp
		150708 SPI1_SCHPO (5-219): 7.81e-78: 234: 88.37		CSE1_SCHPO (3-972): 1.29e-107: 360: 14.83
+	Sc
		745813 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		IMB5_YEAST (1-1046): 8.84e-25: 113: 13.38
+	Sc
		745880 GSP1_YEAST (1-219): 5.79e-77: 232: 100.00		IMB1_YEAST (1-817): 8.65e-19: 94.3: 11.08