Interactor 1: PRS6A (P33297)
26S proteasome regulatory subunit 6A (Tat-binding protein homolog 1) (TBP-1)
Gene: RPT5

Interactor 2: PRS4 (P40327)
26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5)
Gene: RPT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.921

The method score is based on:

Property Details
Experiments 16284124, 37968396, 16554755, 18467557, 31848235
Identification Methods affinity chromatography technology, protein complementation assay, cross-linking study, tandem affinity purification, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB_C~Prot_ATP_ID_OB_C
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 434
Sc

1 437
+ Dm
+ Dm
+ Dm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Af
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc
+ Sc

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Last updated: 11Aug2025