Interactor 1: PLK1 (P34331)
Serine/threonine-protein kinase plk-1 (EC 2.7.11.21) (Polo-like kinase 1)
Gene: plk-1
Interactor 2: BUB1 (Q21776)
Mitotic checkpoint serine/threonine-protein kinase bub-1 (EC 2.7.11.1) (Budding uninhibited by benzimidazole 1)
Gene: bub-1
Species: Caenorhabditis elegans
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.743 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18692475, unassigned701 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0000776 - kinetochore GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0106310 - protein serine kinase activity and 1 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025