HitPredict

Interactor 1: ALXA (P34552)
Apoptosis-linked gene 2-interacting protein X 1 (Prion-like-(Q/N-rich) domain-bearing protein 58) (Protein YNK1)
Gene: alx-1

Interactor 2: Q95PW9 (Q95PW9)
NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
Gene: nck-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 882 Ce			1 395
+	Hs
		463176 PDC6I_HUMAN (1-878): 0: 739: 37.09		YES_HUMAN (213-375): 1e-53: 188: 34.68
+	Hs
		1357015 PDC6I_HUMAN (1-878): 0: 739: 37.09		ITSN2_HUMAN (8-285): 3.76e-34: 136: 19.61
+	Hs
		1154143 PDC6I_HUMAN (1-878): 0: 739: 37.09		ITSN1_HUMAN (5-269): 4.52e-32: 130: 14.77
+	Hs
		987797 PDC6I_HUMAN (1-878): 0: 739: 37.09		GRB2_HUMAN (5-175): 2.31e-28: 112: 20.37
+	Mm
		1221266 PDC6I_MOUSE (1-878): 0: 727: 37.20		GRB2_MOUSE (5-175): 1.69e-28: 112: 20.83
+	Hs
		473450 PDC6I_HUMAN (1-878): 0: 739: 37.09		HCK_HUMAN (2-186): 3.98e-18: 87.9: 16.13
+	Hs
		440648 PDC6I_HUMAN (1-878): 0: 739: 37.09		FYN_HUMAN (6-108): 2.98e-17: 85.2: 19.05
+	Mm
		431378 PDC6I_MOUSE (1-878): 0: 727: 37.20		SRC_MOUSE (6-108): 7.94e-16: 80.9: 20.00
+	Hs
		557401 PDC6I_HUMAN (1-878): 0: 739: 37.09		SRC_HUMAN (6-108): 1.01e-11: 68.5: 20.00
+	Ce
		759619 ALXA_CAEEL (1-882): 0: 706: 100.00		Q9U2T9_CAEEL (2-58): 1.08e-10: 65.5: 26.67
+	Hs
		1154169 PTN23_HUMAN (4-882): 7.6e-178: 558: 21.64		ITSN1_HUMAN (5-269): 4.52e-32: 130: 14.77
+	Hs
		987935 PTN23_HUMAN (4-882): 7.6e-178: 558: 21.64		GRB2_HUMAN (5-175): 2.31e-28: 112: 20.37
+	Hs
		557470 PTN23_HUMAN (4-882): 7.6e-178: 558: 21.64		SRC_HUMAN (6-108): 1.01e-11: 68.5: 20.00
+	Dm
		1061466 Q9VUH6_DROME (6-881): 4.13e-148: 481: 21.47		GRAP_DROME (2-59): 7.19e-16: 77.9: 27.59
+	Hs
		222087 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		NCK2_HUMAN (2-393): 1.76e-85: 266: 37.82
+	Hs
		463102 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		YES_HUMAN (213-375): 1e-53: 188: 34.68
+	Hs
		169499 HGS_HUMAN (538-882): 3.71e-27: 120: 11.97		GRB2_HUMAN (5-175): 2.31e-28: 112: 20.37
+	Hs
		63181 VP37C_HUMAN (536-875): 3.46e-25: 109: 11.08		GRB2_HUMAN (5-175): 2.31e-28: 112: 20.37
+	Hs
		987659 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		GRB2_HUMAN (5-175): 2.31e-28: 112: 20.37
+	Hs
		440773 MAGL2_HUMAN (700-882): 2.64e-11: 69.9: 15.43		FYN_HUMAN (6-108): 2.98e-17: 85.2: 19.05