HitPredict

Interactor 1: GRIK1 (P39086)
Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5)
Gene: GRIK1

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12597860
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 918 Hs			1 1128
+	Hs
		1022369 GRIK2_HUMAN (6-909): 0: 885: 76.46		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		786717 GRIA1_HUMAN (14-913): 0: 776: 37.08		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		816229 GRIA4_HUMAN (20-918): 0: 765: 35.79		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		786768 GRIA3_HUMAN (1-904): 0: 760: 35.88		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Rn
		585145 GRIA1_RAT (14-913): 0: 770: 36.83		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585210 GRIA4_RAT (20-918): 0: 766: 35.79		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Hs
		761199 GRIK1_HUMAN (1-918): 0: 961: 100.00		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Hs
		1021483 GRIK2_HUMAN (6-909): 0: 885: 76.46		DLG1_HUMAN (9-377): 2.52e-17: 89.7: 13.17
+	Hs
		1022366 GRIK2_HUMAN (6-909): 0: 885: 76.46		DLG3_HUMAN (803-1120): 7.46e-15: 81.7: 14.15
+	Hs
		942335 GRIK2_HUMAN (6-909): 0: 885: 76.46		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Rn
		677766 GRIK2_RAT (12-909): 0: 881: 76.64		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		761217 GRIK2_MOUSE (12-909): 0: 881: 76.64		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		786696 GRIA1_HUMAN (14-913): 0: 776: 37.08		DLG1_HUMAN (9-377): 2.52e-17: 89.7: 13.17
+	Rn
		585151 GRIA1_RAT (14-913): 0: 770: 36.83		DLG1_RAT (9-377): 2.47e-15: 83.2: 13.98
+	Rn
		585138 GRIA1_RAT (14-913): 0: 770: 36.83		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		620904 GRIA1_MOUSE (14-913): 0: 767: 36.83		DLG2_MOUSE (998-1124): 1.41e-15: 84: 18.57
+	Mm
		620881 GRIA1_MOUSE (14-913): 0: 767: 36.83		DLG3_MOUSE (792-1120): 2.61e-15: 83.2: 13.99
+	Mm
		1143565 GRIA4_MOUSE (20-918): 0: 767: 36.12		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Mm
		620892 GRIA1_MOUSE (14-913): 0: 767: 36.83		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		786757 GRIA3_HUMAN (1-904): 0: 760: 35.88		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74