HitPredict

Interactor 1: UBC8 (P35131)
Ubiquitin-conjugating enzyme E2 8 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 8) (UBCAT4A) (Ubiquitin carrier protein 8) (Ubiquitin-conjugating enzyme E2-17 kDa 8) (Ubiquitin-protein ligase 8)
Gene: UBC8

Interactor 2: CIP8 (Q9SPL2)
E3 ubiquitin-protein ligase CIP8 (EC 2.3.2.27) (COP1-interacting protein 8) (RING-type E3 ubiquitin transferase CIP8)
Gene: CIP8

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.681

Property	Details
Experiments	12028569
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 148 At			1 334
+	Zm
		77732 B4FC97_MAIZE (1-148): 1.4e-84: 246: 93.24		B6U926_MAIZE (1-321): 1.69e-52: 179: 22.32
+	Zm
		83048 B6SZE0_MAIZE (1-148): 1.37e-84: 246: 93.92		B6U926_MAIZE (1-321): 1.69e-52: 179: 22.32
+	Hs
		1490989 UB2D4_HUMAN (1-147): 1.43e-83: 243: 80.27		RN115_HUMAN (14-333): 2.29e-51: 174: 20.94
+	At
		762767 UBC9_ARATH (1-148): 6.78e-84: 244: 95.95		RNG1L_ARATH (2-331): 1.29e-50: 172: 25.30
+	Hs
		906835 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		RN115_HUMAN (14-333): 2.29e-51: 174: 20.94
+	Hs
		1414950 UB2D4_HUMAN (1-147): 1.43e-83: 243: 80.27		RN126_HUMAN (5-333): 2.03e-49: 169: 22.58
+	Hs
		906765 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		RN126_HUMAN (5-333): 2.03e-49: 169: 22.58
+	Hs
		1252791 UB2D4_HUMAN (1-147): 1.43e-83: 243: 80.27		RN111_HUMAN (10-309): 2.26e-34: 135: 14.20
+	Hs
		302436 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		RNF8_HUMAN (38-301): 9.13e-36: 136: 10.91
+	Hs
		906684 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		RN111_HUMAN (10-309): 2.26e-34: 135: 14.20
+	Hs
		906829 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		RNF6_HUMAN (124-301): 4.21e-32: 128: 18.79
+	Hs
		1453960 UB2D4_HUMAN (1-147): 1.43e-83: 243: 80.27		RN181_HUMAN (230-327): 1.55e-34: 125: 37.76
+	Hs
		906804 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		RN181_HUMAN (230-327): 1.55e-34: 125: 37.76
+	Hs
		208592 UB2D4_HUMAN (1-147): 1.43e-83: 243: 80.27		PJA2_HUMAN (67-329): 1.94e-29: 120: 16.48
+	Hs
		208482 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		PJA2_HUMAN (67-329): 1.94e-29: 120: 16.48
+	Hs
		208495 UB2D2_HUMAN (1-147): 1.86e-82: 240: 80.27		PJA2_HUMAN (67-329): 1.94e-29: 120: 16.48
+	Hs
		1294294 UB2D4_HUMAN (1-147): 1.43e-83: 243: 80.27		GOLI_HUMAN (233-324): 4.72e-21: 94.9: 32.08
+	Hs
		906695 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		GOLI_HUMAN (233-324): 4.72e-21: 94.9: 32.08
+	Hs
		1461632 UB2D4_HUMAN (1-147): 1.43e-83: 243: 80.27		RN150_HUMAN (233-298): 4.02e-18: 86.4: 34.78
+	Hs
		906823 UB2D1_HUMAN (1-147): 1.11e-82: 241: 76.19		RN150_HUMAN (233-298): 4.02e-18: 86.4: 34.78