HitPredict

Interactor 1: NCS1 (P62166)
Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein)
Gene: NCS1

Interactor 2: M3K21 (Q5TCX8)
Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4)
Gene: MAP3K21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 190 Hs			1 1036
+	Hs
		740665 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K21_HUMAN (1-1036): 0: 701: 100.00
+	Hs
		901307 NCALD_HUMAN (1-184): 1e-52: 168: 60.33		M3K21_HUMAN (1-1036): 0: 701: 100.00
+	Hs
		950455 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K21_HUMAN (1-1036): 0: 701: 100.00
+	Hs
		740655 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K10_HUMAN (32-1021): 0: 570: 44.87
+	Hs
		950449 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K10_HUMAN (32-1021): 0: 570: 44.87
+	Hs
		740653 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K9_HUMAN (38-1036): 0: 561: 47.56
+	Hs
		945769 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K9_HUMAN (38-1036): 0: 561: 47.56
+	Hs
		906758 NCS1_HUMAN (1-190): 3.67e-49: 159: 100.00		M3K9_HUMAN (38-1036): 0: 561: 47.56
+	Hs
		740661 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K11_HUMAN (32-888): 7.63e-141: 445: 44.47
+	Hs
		901304 NCALD_HUMAN (1-184): 1e-52: 168: 60.33		M3K11_HUMAN (32-888): 7.63e-141: 445: 44.47
+	Hs
		950452 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K11_HUMAN (32-888): 7.63e-141: 445: 44.47
+	Hs
		906763 NCS1_HUMAN (1-190): 3.67e-49: 159: 100.00		M3K11_HUMAN (32-888): 7.63e-141: 445: 44.47