HitPredict

Interactor 1: SPT23 (P35210)
Protein SPT23
Gene: SPT23

Interactor 2: RSP5 (P39940)
E3 ubiquitin-protein ligase RSP5 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase RSP5) (Reverses SPT-phenotype protein 5)
Gene: RSP5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 11733065, 11007476, 15466864, 17719829, 19597489, 11870222, 15933713, 17289586
Identification Methods two hybrid, affinity chromatography technology, pull down, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~HECT
Common GO terms GO:0005634 - nucleus
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1082
Sc

1 809
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Service provided by Combinatics, Japan

Last updated: 11Aug2025