HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: UBP13 (Q92995)
Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13)
Gene: USP13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	30323974, 38043062
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 781 Hs			1 863
+	Hs
		764519 CTNB1_HUMAN (1-781): 0: 618: 100.00		UBP5_HUMAN (26-863): 0: 730: 59.81
+	Hs
		764811 CTNB1_HUMAN (1-781): 0: 618: 100.00		UBP39_HUMAN (93-698): 2.13e-76: 261: 13.99
+	Hs
		764944 CTNB1_HUMAN (1-781): 0: 618: 100.00		USP9X_HUMAN (296-701): 9.48e-69: 251: 16.86
+	Mm
		1000338 CTNB1_MOUSE (1-781): 0: 616: 99.87		USP9X_MOUSE (296-701): 9.93e-69: 251: 16.94
+	Hs
		764850 CTNB1_HUMAN (1-781): 0: 618: 100.00		UBP49_HUMAN (188-333): 3.65e-26: 116: 20.55
+	Hs
		288356 CTNB1_HUMAN (1-781): 0: 618: 100.00		UBP2_HUMAN (713-859): 1.92e-21: 101: 17.11
+	Hs
		764505 CTNB1_HUMAN (1-781): 0: 618: 100.00		UBP8_HUMAN (686-861): 9.62e-19: 93.9: 12.64
+	Hs
		764841 CTNB1_HUMAN (1-781): 0: 618: 100.00		U17L2_HUMAN (663-862): 1.15e-18: 92.3: 14.63
+	Hs
		764713 CTNB1_HUMAN (1-781): 0: 618: 100.00		UBP4_HUMAN (460-606): 2.31e-11: 69.8: 16.34
+	Hs
		765099 CTNB1_HUMAN (1-781): 0: 618: 100.00		UBP21_HUMAN (723-859): 1.48e-09: 63.4: 20.71
+	Sc
		893330 IMA1_YEAST (219-692): 2.28e-69: 239: 15.26		UBP8_YEAST (718-859): 3.27e-12: 71.9: 15.39