HitPredict

Interactor 1: RFC1 (P35251)
Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit)
Gene: RFC1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27248496, 30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1148 Hs			1 103
+	Sc
		382074 RFC1_YEAST (268-1148): 5.5e-125: 406: 29.95		H4_YEAST (18-103): 6.16e-41: 132: 90.70
+	Hs
		979855 ATAD2_HUMAN (211-1119): 1.05e-74: 273: 10.83		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		769696 RFC4_HUMAN (557-927): 1.07e-72: 248: 19.47		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Sc
		382073 RFC3_YEAST (572-928): 1.29e-76: 258: 21.25		H4_YEAST (18-103): 6.16e-41: 132: 90.70
+	Mm
		980661 ATAD2_MOUSE (557-1119): 1.4e-61: 231: 11.56		H4_MOUSE (1-103): 1.39e-48: 151: 100.00
+	Sc
		382136 RFC4_YEAST (583-908): 1.26e-73: 249: 20.53		H4_YEAST (18-103): 6.16e-41: 132: 90.70
+	Hs
		829059 RFC5_HUMAN (565-913): 9.57e-65: 225: 19.22		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		769835 RFC2_HUMAN (560-915): 1.88e-62: 218: 18.21		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Sc
		382138 RFC2_YEAST (565-884): 1.39e-61: 216: 18.98		H4_YEAST (18-103): 6.16e-41: 132: 90.70
+	Hs
		980173 ATAD5_HUMAN (494-707): 4.09e-36: 151: 25.96		H4_HUMAN (1-103): 1.39e-48: 151: 100.00