HitPredict

Interactor 1: DRD3 (P35462)
D(3) dopamine receptor (Dopamine D3 receptor)
Gene: DRD3

Interactor 2: SH3G2 (Q99962)
Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2)
Gene: SH3GL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25517094
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 352
+	Hs
		771645 DRD3_HUMAN (1-400): 1.09e-95: 293: 100.00		SH3G3_HUMAN (1-352): 2.72e-90: 276: 65.63
+	Hs
		771643 DRD3_HUMAN (1-400): 1.09e-95: 293: 100.00		SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57
+	Hs
		612349 ADA2B_HUMAN (38-399): 8.85e-74: 238: 28.40		SH3G2_HUMAN (1-352): 4.28e-96: 291: 100.00
+	Mm
		958593 DRD2_MOUSE (3-400): 1.74e-73: 237: 44.27		SH3G2_MOUSE (1-352): 2.57e-95: 289: 98.86
+	Hs
		466956 ACM4_HUMAN (3-400): 1.68e-71: 233: 21.70		SH3G2_HUMAN (1-352): 4.28e-96: 291: 100.00
+	Hs
		477195 ADA2A_HUMAN (1-399): 1.54e-69: 228: 28.80		SH3G2_HUMAN (1-352): 4.28e-96: 291: 100.00
+	Hs
		466855 ACM2_HUMAN (20-400): 8.25e-66: 218: 22.05		SH3G2_HUMAN (1-352): 4.28e-96: 291: 100.00
+	Hs
		466957 ACM4_HUMAN (3-400): 1.68e-71: 233: 21.70		SH3G3_HUMAN (1-352): 2.72e-90: 276: 65.63
+	Hs
		477196 ADA2A_HUMAN (1-399): 1.54e-69: 228: 28.80		SH3G3_HUMAN (1-352): 2.72e-90: 276: 65.63
+	Hs
		612348 ADA2B_HUMAN (38-399): 8.85e-74: 238: 28.40		SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57
+	Hs
		466955 ACM4_HUMAN (3-400): 1.68e-71: 233: 21.70		SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57
+	Hs
		477194 ADA2A_HUMAN (1-399): 1.54e-69: 228: 28.80		SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57
+	Hs
		1408405 HRH3_HUMAN (43-399): 1.72e-56: 193: 23.70		SH3G2_HUMAN (1-352): 4.28e-96: 291: 100.00
+	Hs
		466854 ACM2_HUMAN (20-400): 8.25e-66: 218: 22.05		SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57
+	Hs
		1408387 HRH3_HUMAN (43-399): 1.72e-56: 193: 23.70		SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57
+	Hs
		771631 DRD3_HUMAN (1-400): 1.09e-95: 293: 100.00		GRB2_HUMAN (295-351): 1.52e-12: 67.8: 43.10
+	Mm
		958595 DRD2_MOUSE (3-400): 1.74e-73: 237: 44.27		SH3K1_MOUSE (280-347): 3.74e-10: 63.2: 44.00
+	Hs
		732921 GASR_HUMAN (2-397): 1.32e-57: 196: 20.24		GRB2_HUMAN (295-351): 1.52e-12: 67.8: 43.10
+	Hs
		641886 DRD4_HUMAN (38-400): 2.24e-54: 187: 38.42		GRB2_HUMAN (295-351): 1.52e-12: 67.8: 43.10