HitPredict

Interactor 1: FBN1 (P35555)
Fibrillin-1 [Cleaved into: Asprosin]
Gene: FBN1

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.50	0.593

Property	Details
Experiments	32984335, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2871 Hs			1 296
+	Hs
		772349 FBN2_HUMAN (1-1850): 5.95e-124: 442: 24.70		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		772343 FBN2_HUMAN (1-1850): 5.95e-124: 442: 24.70		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1047775 NOTC2_HUMAN (1-974): 2.25e-59: 230: 15.05		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1460866 JAG2_HUMAN (2357-2781): 3.55e-31: 137: 14.55		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1008029 JAG1_HUMAN (3-498): 3.23e-27: 124: 12.87		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1449504 TEN2_HUMAN (2529-2757): 4.39e-26: 120: 16.16		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1454331 TEN3_HUMAN (2565-2810): 2.79e-22: 108: 9.35		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1460861 NOTC3_HUMAN (8-463): 6.78e-21: 103: 14.43		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		857586 NOTC1_HUMAN (3-413): 6.34e-15: 83.9: 13.58		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1294394 FRAS1_HUMAN (6-502): 6.15e-14: 80.9: 8.45		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1353094 SNED1_HUMAN (2-284): 3.47e-13: 78.2: 13.23		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1132069 LTBP1_HUMAN (1-561): 1.14e-12: 76.6: 16.40		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1324546 LTBP4_HUMAN (12-575): 1.21e-12: 76.2: 16.95		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		666734 TENA_HUMAN (2-147): 2.83e-10: 68.5: 14.97		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1448276 LTBP3_HUMAN (2-655): 2.05e-16: 88.6: 14.77		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1294387 FRAS1_HUMAN (6-502): 6.15e-14: 80.9: 8.45		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1132064 LTBP1_HUMAN (1-561): 1.14e-12: 76.6: 16.40		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1324540 LTBP4_HUMAN (12-575): 1.21e-12: 76.2: 16.95		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		654559 FBLN1_HUMAN (224-363): 4.17e-12: 73.9: 34.75		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		666731 TENA_HUMAN (2-147): 2.83e-10: 68.5: 14.97		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81