HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	29884807, 27460707
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RanBP
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 526 Hs			1 282
+	Hs
		988172 RBP56_HUMAN (42-460): 2.96e-42: 161: 48.10		TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25
+	Hs
		1102042 RBP56_HUMAN (42-460): 2.96e-42: 161: 48.10		PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49
+	Hs
		550392 RBP56_HUMAN (42-460): 2.96e-42: 161: 48.10		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		774994 FUS_HUMAN (1-526): 5.12e-39: 150: 100.00		TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25
+	Hs
		550147 FUS_HUMAN (1-526): 5.12e-39: 150: 100.00		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		775060 FUS_HUMAN (1-526): 5.12e-39: 150: 100.00		PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49
+	Hs
		1032944 EWS_HUMAN (3-451): 4.67e-30: 126: 31.05		TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00
+	Hs
		988089 EWS_HUMAN (3-451): 4.67e-30: 126: 31.05		TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25
+	Hs
		988235 PPIE_HUMAN (280-514): 2.72e-31: 124: 19.84		TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25
+	Hs
		550522 PPIE_HUMAN (280-514): 2.72e-31: 124: 19.84		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		775219 FUS_HUMAN (1-526): 5.12e-39: 150: 100.00		PPIL4_HUMAN (117-195): 7.76e-27: 110: 39.24
+	Hs
		1102145 RBM8A_HUMAN (219-366): 3.36e-27: 109: 26.35		PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49
+	Hs
		550546 RBM8A_HUMAN (219-366): 3.36e-27: 109: 26.35		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		1101941 PABP4_HUMAN (280-379): 4.84e-13: 73.5: 22.00		TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00
+	Dm
		95153 E1JI93_DROME (59-284): 5.2e-13: 74.3: 17.70		TRA2_DROME (97-281): 1.36e-44: 153: 43.78
+	Mm
		953827 Q8BQ46_MOUSE (42-460): 2.88e-40: 155: 48.34		CIRBP_MOUSE (121-193): 1.31e-10: 60.8: 58.90
+	Hs
		550262 PABP4_HUMAN (280-379): 4.84e-13: 73.5: 22.00		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		726754 EWS_HUMAN (3-451): 4.67e-30: 126: 31.05		TIA1_HUMAN (114-207): 1.65e-18: 86.4: 21.28
+	Mm
		915302 EWS_MOUSE (3-451): 2.27e-29: 124: 35.56		TIA1_MOUSE (114-207): 2.25e-18: 86: 21.28
+	At
		102031 TAF15_ARATH (281-452): 1.3e-39: 149: 34.30		SUA_ARATH (117-197): 2.19e-09: 60.2: 37.35