HitPredict

Interactor 1: ID4 (P41139)
DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4) (Inhibitor of differentiation 4)
Gene: ID4

Interactor 2: OLIG1 (Q9JKN5)
Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte-specific bHLH transcription factor 1)
Gene: OLIG1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.683

Property	Details
Experiments	15280210
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046983 - protein dimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 161 Mm			1 260
+	Hs
		814911 ID4_HUMAN (1-161): 1.99e-63: 193: 98.14		OLIG1_HUMAN (1-260): 8.02e-49: 164: 81.18
+	Mm
		781011 ID2_MOUSE (1-148): 6.15e-43: 140: 41.89		OLIG1_MOUSE (1-260): 5e-55: 179: 100.00
+	Hs
		970588 ID2_HUMAN (1-148): 1.31e-42: 140: 42.57		OLIG1_HUMAN (1-260): 8.02e-49: 164: 81.18
+	Hs
		814916 ID4_HUMAN (1-161): 1.99e-63: 193: 98.14		NGN3_HUMAN (22-228): 1.27e-28: 109: 23.72
+	Hs
		524549 ID4_HUMAN (1-161): 1.99e-63: 193: 98.14		LYL1_HUMAN (12-223): 6.41e-27: 107: 22.64
+	Hs
		546072 ID4_HUMAN (1-161): 1.99e-63: 193: 98.14		MYOG_HUMAN (23-221): 7.03e-27: 105: 15.84
+	Hs
		814906 ID4_HUMAN (1-161): 1.99e-63: 193: 98.14		OLIG2_HUMAN (4-259): 2.45e-25: 103: 23.90
+	Hs
		616610 ID4_HUMAN (1-161): 1.99e-63: 193: 98.14		MYF6_HUMAN (20-201): 1.25e-25: 102: 17.39
+	Mm
		781013 ID4_MOUSE (1-161): 1.17e-62: 191: 100.00		OLIG2_MOUSE (4-259): 5.02e-25: 102: 23.90
+	Hs
		524547 ID1_HUMAN (12-161): 7.47e-53: 166: 37.42		LYL1_HUMAN (12-223): 6.41e-27: 107: 22.64
+	Hs
		526742 ID1_HUMAN (12-161): 7.47e-53: 166: 37.42		MYF5_HUMAN (23-202): 1.72e-26: 105: 15.05
+	Hs
		546071 ID1_HUMAN (12-161): 7.47e-53: 166: 37.42		MYOG_HUMAN (23-221): 7.03e-27: 105: 15.84
+	Hs
		526743 ID2_HUMAN (1-148): 1.31e-42: 140: 42.57		MYF5_HUMAN (23-202): 1.72e-26: 105: 15.05
+	Hs
		970566 ID2_HUMAN (1-148): 1.31e-42: 140: 42.57		OLIG2_HUMAN (4-259): 2.45e-25: 103: 23.90
+	Mm
		781010 ID2_MOUSE (1-148): 6.15e-43: 140: 41.89		OLIG2_MOUSE (4-259): 5.02e-25: 102: 23.90
+	Hs
		524557 ID3_HUMAN (1-135): 5.52e-34: 117: 42.96		LYL1_HUMAN (12-223): 6.41e-27: 107: 22.64
+	Hs
		526744 ID3_HUMAN (1-135): 5.52e-34: 117: 42.96		MYF5_HUMAN (23-202): 1.72e-26: 105: 15.05