HitPredict

Interactor 1: PCDB3 (Q9Y5E6)
Protocadherin beta-3 (PCDH-beta-3)
Gene: PCDHB3

Interactor 2: PCDG5 (Q9Y5G8)
Protocadherin gamma-A5 (PCDH-gamma-A5)
Gene: PCDHGA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 931
+	Hs
		1377976 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDGH_HUMAN (24-916): 0: 1039: 53.53
+	Hs
		1377980 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDC2_HUMAN (25-904): 0: 989: 39.44
+	Hs
		1377960 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDB9_HUMAN (12-773): 0: 625: 47.97
+	Hs
		1357385 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDBA_HUMAN (12-777): 0: 613: 46.75
+	Hs
		1377961 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDB7_HUMAN (27-773): 0: 601: 46.95
+	Hs
		1344890 PCDBG_HUMAN (1-776): 0: 1046: 77.58		PCDBA_HUMAN (12-777): 0: 613: 46.75
+	Hs
		1344892 PCDBG_HUMAN (1-776): 0: 1046: 77.58		PCDB7_HUMAN (27-773): 0: 601: 46.95
+	Hs
		1303074 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDBI_HUMAN (63-791): 0: 576: 45.34
+	Hs
		1377977 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDGE_HUMAN (2-444): 1.58e-96: 326: 26.58
+	Hs
		1377979 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDGA_HUMAN (2-444): 1.62e-95: 323: 26.52
+	Hs
		1377975 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDBD_HUMAN (2-466): 2.98e-94: 317: 24.79
+	Hs
		1377974 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDB2_HUMAN (2-456): 7.49e-91: 308: 25.96
+	Hs
		1377971 PCDB5_HUMAN (1-796): 0: 1055: 75.63		PCDBB_HUMAN (2-456): 1.4e-87: 299: 24.95
+	Hs
		1377970 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDB5_HUMAN (1-234): 1.66e-31: 134: 18.62
+	Hs
		1377973 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDB4_HUMAN (1-234): 5.68e-31: 132: 18.22
+	Hs
		1344894 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDBG_HUMAN (1-256): 5.42e-30: 129: 18.22
+	Hs
		1357384 PCDB3_HUMAN (1-796): 0: 1059: 100.00		PCDB8_HUMAN (1-257): 1.95e-28: 124: 18.15
+	Hs
		1344893 PCDBG_HUMAN (1-776): 0: 1046: 77.58		PCDB6_HUMAN (1-234): 2.5e-30: 130: 17.41