HitPredict

Interactor 1: M9PHL4 (M9PHL4)
IST1 homolog (Charged multivesicular body protein 8)
Gene: Ist1

Interactor 2: Q9VRJ5 (Q9VRJ5)
Charged multivesicular body protein 2b (LD36173p)
Gene: CHMP2B

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ist1~Snf7
Common GO terms	GO:0015031 - protein transport GO:0032509 - endosome transport via multivesicular body sorting pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 384 Dm			1 212
+	Dm
		122094 M9PHL4_DROME (1-384): 3.64e-137: 398: 100.00		Q95SH2_DROME (14-212): 1.22e-35: 126: 19.10
+	Dm
		122098 M9PHL4_DROME (1-384): 3.64e-137: 398: 100.00		Q9VBI3_DROME (2-202): 1.54e-33: 122: 33.83
+	Dm
		122092 M9PHL4_DROME (1-384): 3.64e-137: 398: 100.00		CHM4_DROME (1-187): 3.64e-32: 117: 15.87
+	Dm
		122101 M9PHL4_DROME (1-384): 3.64e-137: 398: 100.00		Q9VN02_DROME (8-211): 1.01e-31: 116: 24.54
+	Dm
		122106 M9PHL4_DROME (1-384): 3.64e-137: 398: 100.00		CHMP5_DROME (2-193): 1.93e-31: 115: 14.07
+	Dm
		1484930 Q9VRY6_DROME (1-384): 3.89e-124: 366: 91.85		Q9VRJ5_DROME (1-212): 4.67e-43: 145: 100.00
+	Dm
		1377978 Q9VRY6_DROME (1-384): 3.89e-124: 366: 91.85		Q95SH2_DROME (14-212): 1.22e-35: 126: 19.10
+	Dm
		1469212 Q9VRY6_DROME (1-384): 3.89e-124: 366: 91.85		Q9VBI3_DROME (2-202): 1.54e-33: 122: 33.83
+	Dm
		1345402 Q9VRY6_DROME (1-384): 3.89e-124: 366: 91.85		CHM4_DROME (1-187): 3.64e-32: 117: 15.87
+	Dm
		1482282 Q9VRY6_DROME (1-384): 3.89e-124: 366: 91.85		Q9VN02_DROME (8-211): 1.01e-31: 116: 24.54
+	Dm
		1485262 Q9VRY6_DROME (1-384): 3.89e-124: 366: 91.85		CHMP5_DROME (2-193): 1.93e-31: 115: 14.07
+	Hs
		925655 IST1_HUMAN (1-383): 6.85e-109: 325: 46.13		CHM1B_HUMAN (16-210): 1.46e-35: 126: 15.39
+	Hs
		925688 IST1_HUMAN (1-383): 6.85e-109: 325: 46.13		CHMP5_HUMAN (2-198): 3.57e-34: 122: 14.71
+	Hs
		925683 IST1_HUMAN (1-383): 6.85e-109: 325: 46.13		CHM1A_HUMAN (16-210): 1.42e-32: 118: 13.85
+	Hs
		925681 IST1_HUMAN (1-383): 6.85e-109: 325: 46.13		CHM4B_HUMAN (14-207): 8.79e-32: 116: 16.00
+	Ce
		112134 G5EDV6_CAEEL (2-384): 2.98e-98: 300: 38.01		Q18886_CAEEL (1-211): 2.83e-32: 117: 14.75
+	Ce
		112137 G5EDV6_CAEEL (2-384): 2.98e-98: 300: 38.01		Q9TXI3_CAEEL (15-210): 3.11e-32: 117: 17.35
+	Sc
		781331 IST1_YEAST (6-226): 3.95e-62: 203: 25.32		DID4_YEAST (1-197): 3.26e-37: 130: 26.77
+	Sc
		781014 IST1_YEAST (6-226): 3.95e-62: 203: 25.32		VPS24_YEAST (9-205): 5.47e-35: 125: 24.24
+	Sc
		923806 IST1_YEAST (6-226): 3.95e-62: 203: 25.32		DID2_YEAST (16-210): 8.97e-30: 111: 18.27