Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR
Interactor 2: FKB1A (P62942)
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Gene: FKBP1A
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10089303, 15467718, 15268862, 29997244, 8662507, 7822316, 32131492, 35211260, 20851351, 20639890, 15284440, 15796538, 36135776, 17991864, 17148612, 9334222 |
| Identification Methods | x-ray crystallography, affinity chromatography technology, fluorescent resonance energy transfer, pull down, protein complementation assay, two hybrid, beta galactosidase complementation, luminescence based mammalian interactome mapping |
| Interaction Type | association, physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FKBP_C~FRB_dom |
| Common GO terms | GO:0003007 - heart morphogenesis GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
