HitPredict

Interactor 1: NOP4 (P37838)
Nucleolar protein 4 (Nucleolar protein NOP77)
Gene: NOP4

Interactor 2: NOP12 (Q08208)
Nucleolar protein 12
Gene: NOP12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.951

Property	Details
Experiments	11805826, 25877921, 27077951, 37968396, 16429126, unassigned1262
Identification Methods	tandem affinity purification, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 685 Sc			1 459
+	Sc
		791084 NOP4_YEAST (1-685): 7.18e-109: 346: 100.00		NOP13_YEAST (27-400): 8.64e-41: 152: 17.73
+	Hs
		550311 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		PAP1L_HUMAN (175-459): 7.1e-60: 208: 13.19
+	Hs
		550097 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		PABP1_HUMAN (175-459): 1.72e-59: 207: 14.58
+	Hs
		1197178 PABP3_HUMAN (3-146): 1.44e-18: 92: 18.75		PAP1L_HUMAN (175-459): 7.1e-60: 208: 13.19
+	Hs
		550262 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		PABP4_HUMAN (175-459): 2.2e-57: 202: 13.54
+	Zm
		8282 A0A1D6ELH4_MAIZE (3-186): 1.15e-23: 108: 16.04		A0A1D6ELH4_MAIZE (175-459): 3.45e-52: 188: 13.54
+	Hs
		1102095 PABP3_HUMAN (3-146): 1.44e-18: 92: 18.75		PABP4_HUMAN (175-459): 2.2e-57: 202: 13.54
+	Hs
		550464 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		PABP3_HUMAN (175-459): 2.01e-55: 196: 14.58
+	Hs
		550346 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		PABP2_HUMAN (252-400): 7.94e-43: 155: 25.49
+	Hs
		550137 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		TIA1_HUMAN (273-459): 1.48e-33: 131: 12.23
+	Mm
		710979 PABP1_MOUSE (3-165): 7.88e-20: 96: 18.41		TIA1_MOUSE (273-459): 1.48e-33: 131: 12.23
+	Hs
		550250 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		ELAV2_HUMAN (37-360): 2.42e-31: 125: 11.49
+	Hs
		726768 ELAV1_HUMAN (405-633): 7.81e-16: 81.3: 13.42		TIA1_HUMAN (273-459): 1.48e-33: 131: 12.23
+	Dm
		119988 M9PBZ2_DROME (504-629): 1.36e-19: 95.6: 14.29		Q9VYI0_DROME (267-454): 1.01e-26: 112: 12.56
+	Zm
		117407 K7TYT2_MAIZE (462-629): 3.33e-20: 96: 13.69		K7TYT2_MAIZE (263-459): 5.88e-26: 111: 13.64
+	Sp
		153884 PABP_SCHPO (3-126): 1.41e-20: 98.6: 21.77		PAB2_SCHPO (244-360): 4.01e-21: 92: 27.64
+	Sp
		153909 GBP2_SCHPO (28-155): 3.8e-19: 92.9: 16.41		PAB2_SCHPO (244-360): 4.01e-21: 92: 27.64
+	Hs
		550237 PABP1_HUMAN (3-165): 7.74e-20: 96: 18.41		TIAR_HUMAN (8-280): 1.16e-10: 64.9: 8.03
+	Hs
		750423 ELAV1_HUMAN (405-633): 7.81e-16: 81.3: 13.42		CSTF2_HUMAN (269-354): 1.5e-14: 77.7: 28.74