HitPredict

Interactor 1: RANG (P43487)
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)
Gene: RANBP1

Interactor 2: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Hs			1 1817
+	Hs
		483390 RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80		NUP98_HUMAN (1-1817): 0: 1506: 100.00
+	Hs
		858070 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		NUP98_HUMAN (1-1817): 0: 1506: 100.00
+	Hs
		796707 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		NU153_HUMAN (1-241): 3.42e-12: 74: 18.78
+	Hs
		727218 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		NU214_HUMAN (162-710): 1.58e-09: 65.4: 16.40
+	Hs
		639543 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		CO5A3_HUMAN (1-350): 3.83e-09: 64: 11.08
+	Hs
		152767 RGPD8_HUMAN (1-201): 9.54e-47: 166: 34.31		NU153_HUMAN (1-241): 3.42e-12: 74: 18.78
+	Hs
		834562 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		NU153_HUMAN (1-241): 3.42e-12: 74: 18.78
+	Hs
		727224 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		NU214_HUMAN (162-710): 1.58e-09: 65.4: 16.40
+	Sc
		691658 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		NU116_YEAST (3-603): 7.9e-21: 102: 16.28
+	Sc
		775017 YRB2_YEAST (2-155): 4.17e-27: 106: 23.23		NU116_YEAST (3-603): 7.9e-21: 102: 16.28
+	Sc
		691657 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		NU100_YEAST (147-754): 1.94e-18: 94.4: 11.51
+	Sc
		691636 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		NU159_YEAST (2-750): 1.85e-16: 88.3: 12.60
+	Hs
		1350244 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		CHD7_HUMAN (11-485): 3.03e-16: 87.9: 9.39
+	Sc
		541854 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		NSP1_YEAST (1-541): 6.79e-15: 82.5: 13.95
+	Sc
		691655 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		NUP49_YEAST (1-184): 2.29e-13: 76.6: 27.60
+	Hs
		727317 RANB3_HUMAN (10-186): 4.16e-30: 117: 16.75		NU214_HUMAN (162-710): 1.58e-09: 65.4: 16.40
+	Hs
		834685 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		NU153_HUMAN (1-241): 3.42e-12: 74: 18.78
+	Sc
		691641 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		NUP57_YEAST (1-164): 1.9e-10: 67.7: 27.06
+	Hs
		727330 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		NU214_HUMAN (162-710): 1.58e-09: 65.4: 16.40
+	Hs
		1293168 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		P121A_HUMAN (2-326): 2.46e-09: 64.8: 14.42