HitPredict

Interactor 1: MP2K4 (P45985)
Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)
Gene: MAP2K4

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 399 Hs			1 783
+	Hs
		682189 AKT2_HUMAN (57-399): 3.9e-126: 374: 20.86		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		681909 AKT1_HUMAN (74-399): 9.1e-126: 373: 19.22		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		568710 KAPCA_HUMAN (91-399): 1.73e-121: 357: 18.41		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		610741 KAPCB_HUMAN (92-399): 1.55e-121: 357: 19.43		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		625496 CDK2_HUMAN (99-378): 8.94e-122: 356: 22.62		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		805440 MP2K3_HUMAN (22-387): 5.5e-121: 356: 46.72		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1023065 STK4_HUMAN (73-395): 1.9e-112: 339: 30.25		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		153141 MP2K7_HUMAN (48-394): 7.51e-113: 338: 45.87		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1047941 KCC1A_HUMAN (99-387): 1.88e-112: 335: 21.92		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1027387 STK3_HUMAN (68-386): 1.49e-102: 314: 31.25		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1026180 PAK1_HUMAN (19-368): 1.08e-99: 308: 28.06		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172483 STK24_HUMAN (72-387): 1.03e-99: 305: 32.81		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		734962 MP2K2_HUMAN (100-393): 3.95e-62: 206: 37.24		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		568758 KAPCA_HUMAN (91-399): 1.73e-121: 357: 18.41		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		568786 KAPCA_HUMAN (91-399): 1.73e-121: 357: 18.41		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		1026219 PAK1_HUMAN (19-368): 1.08e-99: 308: 28.06		FSD1_HUMAN (345-775): 1.45e-80: 268: 21.72
+	Hs
		584875 CDK2_HUMAN (99-378): 8.94e-122: 356: 22.62		RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81
+	Hs
		536810 PAK1_HUMAN (19-368): 1.08e-99: 308: 28.06		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		537109 STK26_HUMAN (98-388): 2.17e-98: 301: 32.88		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		131546 STK25_HUMAN (85-387): 5.86e-98: 300: 32.46		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77