HitPredict

Interactor 1: DYN1 (P39053)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: Dnm1

Interactor 2: SH3K1 (Q8R550)
SH3 domain-containing kinase-binding protein 1 (Regulator of ubiquitous kinase) (Ruk) (SH3-containing, expressed in tumorigenic astrocytes)
Gene: Sh3kbp1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20551902
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030139 - endocytic vesicle GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 867 Mm			1 709
+	Hs
		1050705 DYN1_HUMAN (1-845): 0: 1050: 99.65		SH3K1_HUMAN (1-709): 4.14e-126: 391: 88.15
+	Mm
		810555 DYN2_MOUSE (1-845): 0: 985: 78.28		SH3K1_MOUSE (1-709): 1.46e-138: 425: 100.00
+	Mm
		237068 DYN1_MOUSE (1-867): 0: 1086: 100.00		NCK2_MOUSE (97-445): 9.08e-27: 114: 12.92
+	Hs
		896808 DYN2_HUMAN (1-845): 0: 983: 77.93		SH3R1_HUMAN (3-694): 3.05e-58: 214: 13.77
+	Hs
		593970 DYN1_HUMAN (1-845): 0: 1050: 99.65		NCK1_HUMAN (102-446): 5.59e-32: 130: 15.58
+	Mm
		810542 DYN1_MOUSE (1-867): 0: 1086: 100.00		ITSN1_MOUSE (1-131): 1.67e-14: 79.7: 24.43
+	Hs
		222060 DYN1_HUMAN (1-845): 0: 1050: 99.65		NCK2_HUMAN (97-446): 1.59e-26: 114: 13.17
+	Hs
		1050684 DYN1_HUMAN (1-845): 0: 1050: 99.65		ITSN1_HUMAN (1-131): 4.91e-16: 84.7: 24.43
+	Rn
		638964 DYN1_RAT (1-845): 0: 1042: 98.34		ITSN1_RAT (1-131): 1.81e-14: 79.7: 24.43
+	Hs
		1050693 DYN1_HUMAN (1-845): 0: 1050: 99.65		DNMBP_HUMAN (47-371): 4.56e-11: 68.6: 12.28
+	Hs
		1050698 DYN1_HUMAN (1-845): 0: 1050: 99.65		NOSTN_HUMAN (289-373): 1.12e-10: 66.6: 40.00
+	Hs
		1050711 DYN1_HUMAN (1-845): 0: 1050: 99.65		SH3G2_HUMAN (296-370): 1.42e-09: 62.4: 44.00
+	Rn
		204807 DYN1_RAT (1-845): 0: 1042: 98.34		SRBS2_RAT (276-507): 1.18e-10: 67.4: 19.51
+	Rn
		204407 DYN1_RAT (1-845): 0: 1042: 98.34		SH3G2_RAT (296-370): 1.84e-09: 62: 42.67
+	Hs
		896780 DYN2_HUMAN (1-845): 0: 983: 77.93		SH319_HUMAN (5-376): 2.47e-22: 104: 17.20
+	Hs
		292819 DYN2_HUMAN (1-845): 0: 983: 77.93		GRAP2_HUMAN (1-57): 2.16e-17: 85.9: 33.33
+	Hs
		896763 DYN2_HUMAN (1-845): 0: 983: 77.93		ITSN1_HUMAN (1-131): 4.91e-16: 84.7: 24.43
+	Mm
		810562 DYN2_MOUSE (1-845): 0: 985: 78.28		ITSN1_MOUSE (1-131): 1.67e-14: 79.7: 24.43
+	Hs
		896800 DYN2_HUMAN (1-845): 0: 983: 77.93		DNMBP_HUMAN (47-371): 4.56e-11: 68.6: 12.28
+	Rn
		204808 DYN2_RAT (1-845): 0: 984: 78.16		SRBS2_RAT (276-507): 1.18e-10: 67.4: 19.51