Interactor 1: ZO1 (P39447)
Tight junction protein 1 (Tight junction protein ZO-1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: Tjp1
Interactor 2: ACTN4 (P57780)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16944923 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Spectrin~ZU5 |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005911 - cell-cell junction |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025