HitPredict

Interactor 1: CDN1A (P39689)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein) (p21)
Gene: Cdkn1a

Interactor 2: CDK2 (P97377)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
Gene: CDK2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 15107404, 18729080, 31112565, 18356301, 15155733, 9488036, 12970760, 10348346, 16982699
Identification Methods affinity chromatography technology, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007265 - Ras protein signal transduction
GO:0030332 - cyclin binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 159
Mm

1 346
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+ Rn
+ Xl
+ Xl
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+ Xl
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+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025