HitPredict

Interactor 1: EIF3I (P40217)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 39 kDa subunit) (eIF-3 39 kDa subunit) (eIF3 p39)
Gene: TIF34

Interactor 2: DUF1 (Q99247)
DUB-associated factor 1
Gene: DUF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 347 Sc			1 1116
+	Sc
		673545 NLE1_YEAST (1-223): 1.64e-45: 164: 16.23		NLE1_YEAST (160-531): 1.43e-52: 195: 13.22
+	Sc
		792078 EIF3I_YEAST (1-347): 1.57e-87: 268: 100.00		GBLP_YEAST (219-509): 1.08e-16: 84.5: 11.30
+	Hs
		992873 POC1B_HUMAN (48-344): 2.18e-74: 239: 14.67		RACK1_HUMAN (361-527): 4.96e-09: 61.3: 7.35
+	Hs
		1450936 NLE1_HUMAN (179-340): 3.41e-37: 140: 13.61		NLE1_HUMAN (251-588): 2.29e-33: 137: 10.63
+	Hs
		1380064 FBXW7_HUMAN (80-346): 5.22e-51: 182: 12.13		FBXW7_HUMAN (346-535): 5.47e-17: 88.3: 12.75
+	Hs
		965141 FBXW7_HUMAN (80-346): 5.22e-51: 182: 12.13		WDR5_HUMAN (1-116): 3.17e-13: 74: 10.08
+	Hs
		965071 WDR5B_HUMAN (127-346): 1.3e-49: 170: 15.25		WDR5_HUMAN (1-116): 3.17e-13: 74: 10.08
+	Hs
		992900 FBXW7_HUMAN (80-346): 5.22e-51: 182: 12.13		RACK1_HUMAN (361-527): 4.96e-09: 61.3: 7.35
+	Hs
		965276 NLE1_HUMAN (179-340): 3.41e-37: 140: 13.61		WDR5_HUMAN (1-116): 3.17e-13: 74: 10.08
+	Hs
		992995 NLE1_HUMAN (179-340): 3.41e-37: 140: 13.61		RACK1_HUMAN (361-527): 4.96e-09: 61.3: 7.35
+	Hs
		845250 LIS1_HUMAN (1-82): 2.06e-22: 99: 30.49		LIS1_HUMAN (351-544): 6.51e-20: 95.6: 10.50
+	Mm
		988931 LIS1_MOUSE (1-82): 1.85e-22: 99: 30.49		LIS1_MOUSE (351-544): 6.34e-20: 95.6: 10.50
+	Hs
		773471 WDR5_HUMAN (227-347): 2.39e-20: 92.1: 8.13		COPB2_HUMAN (20-384): 1.57e-20: 99: 11.96
+	Hs
		965151 SNR40_HUMAN (3-122): 3.79e-27: 111: 17.83		WDR5_HUMAN (1-116): 3.17e-13: 74: 10.08
+	Hs
		845264 LIS1_HUMAN (1-82): 2.06e-22: 99: 30.49		WDR5_HUMAN (1-116): 3.17e-13: 74: 10.08
+	Hs
		992907 SNR40_HUMAN (3-122): 3.79e-27: 111: 17.83		RACK1_HUMAN (361-527): 4.96e-09: 61.3: 7.35
+	Hs
		964797 WDR5_HUMAN (227-347): 2.39e-20: 92.1: 8.13		WDR5_HUMAN (1-116): 3.17e-13: 74: 10.08
+	Hs
		845282 LIS1_HUMAN (1-82): 2.06e-22: 99: 30.49		RACK1_HUMAN (361-527): 4.96e-09: 61.3: 7.35
+	Hs
		964829 WDR5_HUMAN (227-347): 2.39e-20: 92.1: 8.13		RACK1_HUMAN (361-527): 4.96e-09: 61.3: 7.35