HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: X2JDH0 (X2JDH0)
Radish, isoform I
Gene: rsh

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15710747
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap-GAP_dimer~Ras, Rap_GAP~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 192 Dm			1 1799
+	Dm
		828046 RAC1_DROME (1-192): 1.62e-82: 244: 100.00		X2JJU0_DROME (25-1774): 0: 2587: 99.83
+	Hs
		244563 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		SI1L3_HUMAN (673-1089): 2.94e-129: 448: 31.79
+	Hs
		988604 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		SIPA1_HUMAN (735-1090): 5.66e-122: 413: 35.25
+	Hs
		988447 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RGPA1_HUMAN (664-1099): 1.28e-111: 397: 21.38
+	Hs
		962371 RHOA_HUMAN (5-192): 1.2e-76: 229: 54.79		SIPA1_HUMAN (735-1090): 5.66e-122: 413: 35.25
+	Hs
		1233142 RHOJ_HUMAN (2-190): 4.29e-80: 239: 60.32		RGPA1_HUMAN (664-1099): 1.28e-111: 397: 21.38
+	Hs
		1015524 RHOG_HUMAN (1-192): 3.53e-78: 233: 67.19		RGPA1_HUMAN (664-1099): 1.28e-111: 397: 21.38
+	Hs
		953508 RAC3_HUMAN (1-191): 4.3e-78: 233: 89.53		RGPA1_HUMAN (664-1099): 1.28e-111: 397: 21.38
+	Hs
		955292 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		RGPA1_HUMAN (664-1099): 1.28e-111: 397: 21.38
+	Hs
		962161 RHOA_HUMAN (5-192): 1.2e-76: 229: 54.79		RGPA1_HUMAN (664-1099): 1.28e-111: 397: 21.38
+	Hs
		601333 RHOQ_HUMAN (4-192): 1.02e-74: 225: 62.05		RGPA1_HUMAN (664-1099): 1.28e-111: 397: 21.38
+	Hs
		1179637 RHOJ_HUMAN (2-190): 4.29e-80: 239: 60.32		RGPA2_HUMAN (681-1104): 8.97e-102: 365: 18.22
+	Hs
		1015479 RHOG_HUMAN (1-192): 3.53e-78: 233: 67.19		RGPA2_HUMAN (681-1104): 8.97e-102: 365: 18.22
+	Hs
		601310 RHOQ_HUMAN (4-192): 1.02e-74: 225: 62.05		RGPA2_HUMAN (681-1104): 8.97e-102: 365: 18.22
+	Hs
		962650 RHOA_HUMAN (5-192): 1.2e-76: 229: 54.79		KLH20_HUMAN (1436-1719): 3.29e-69: 247: 18.40