HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: RGPA2 (Q2PPJ7)
Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220)
Gene: RALGAPA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1873
+	Hs
		1179637 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		RGPA2_HUMAN (1-1873): 0: 2869: 100.00
+	Hs
		1015479 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		RGPA2_HUMAN (1-1873): 0: 2869: 100.00
+	Hs
		1233142 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		601333 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		988447 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		1015524 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		962161 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		953508 RAC3_HUMAN (10-183): 3.69e-76: 228: 66.67		RGPA1_HUMAN (1-851): 0: 1225: 48.66
+	Hs
		1293041 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		RLGPB_HUMAN (993-1802): 3.67e-139: 473: 17.54
+	Hs
		601355 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		RLGPB_HUMAN (993-1802): 3.67e-139: 473: 17.54
+	Hs
		988497 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		RLGPB_HUMAN (993-1802): 3.67e-139: 473: 17.54
+	Hs
		1015570 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		RLGPB_HUMAN (993-1802): 3.67e-139: 473: 17.54
+	Hs
		962230 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		RLGPB_HUMAN (993-1802): 3.67e-139: 473: 17.54
+	Hs
		953541 RAC3_HUMAN (10-183): 3.69e-76: 228: 66.67		RLGPB_HUMAN (993-1802): 3.67e-139: 473: 17.54
+	Hs
		208649 RHOB_HUMAN (1-204): 2.53e-75: 226: 49.51		SI1L1_HUMAN (1544-1861): 3.58e-92: 335: 19.45
+	Hs
		988604 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		SIPA1_HUMAN (1545-1859): 8.29e-90: 319: 21.23
+	Hs
		962371 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		SIPA1_HUMAN (1545-1859): 8.29e-90: 319: 21.23
+	Hs
		244563 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		SI1L3_HUMAN (1534-1859): 2.79e-83: 306: 20.35
+	Dm
		828043 RAC1_DROME (10-195): 5.51e-77: 230: 63.98		X2JDH0_DROME (1505-1859): 1.78e-80: 297: 18.06
+	Dm
		828046 RAC1_DROME (10-195): 5.51e-77: 230: 63.98		X2JJU0_DROME (1505-1859): 1.66e-80: 297: 18.06