HitPredict

Interactor 1: HNRPU (Q00839)
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120)
Gene: HNRNPU

Interactor 2: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Helicase_C~SPRY
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 825 Hs			1 1430
+	Hs
		962361 HNRPU_HUMAN (1-825): 0: 827: 100.00		DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63
+	Hs
		962369 HNRPU_HUMAN (1-825): 0: 827: 100.00		DHX33_HUMAN (140-476): 6.02e-99: 335: 25.57
+	Hs
		962177 HNRPU_HUMAN (1-825): 0: 827: 100.00		DHX29_HUMAN (139-425): 6.43e-94: 334: 39.32
+	Hs
		962031 HNRPU_HUMAN (1-825): 0: 827: 100.00		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		962172 HNRPU_HUMAN (1-825): 0: 827: 100.00		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39
+	Hs
		994316 HNRL1_HUMAN (6-686): 0: 612: 45.76		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		1092905 HNRL2_HUMAN (6-730): 0: 550: 41.98		DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63
+	Hs
		994190 HNRL2_HUMAN (6-730): 0: 550: 41.98		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		1092847 HNRL2_HUMAN (6-730): 0: 550: 41.98		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39
+	Mm
		1257604 DDX1_MOUSE (257-619): 3.13e-82: 280: 21.15		DHX36_MOUSE (71-521): 8.25e-99: 342: 27.93
+	Hs
		994207 RN123_HUMAN (317-487): 2.68e-40: 163: 23.86		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77