HitPredict

Interactor 1: CDC42 (P40793)
Cdc42 homolog (EC 3.6.5.2)
Gene: CDC42

Interactor 2: M3KSL (Q95UN8)
Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase) (Protein slipper) (dMLK)
Gene: slpr

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 20736302, 20404112
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0005938 - cell cortex
GO:0007165 - signal transduction
GO:0007391 - dorsal closure
GO:0046330 - positive regulation of JNK cascade
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Dm

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Last updated: 11Aug2025