HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: BRPF1 (P55201)
Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)
Gene: BRPF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 1214
+	Hs
		876688 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		BRPF1_HUMAN (1-1214): 0: 1189: 100.00
+	Hs
		319165 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		BRD1_HUMAN (62-1214): 0: 778: 44.59
+	Hs
		934879 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		JADE1_HUMAN (74-656): 7.35e-135: 434: 25.83
+	Hs
		828328 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		JADE3_HUMAN (73-656): 1.19e-118: 389: 25.21
+	Hs
		935056 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		JADE3_HUMAN (73-656): 1.19e-118: 389: 25.21
+	Hs
		935232 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		KDM4C_HUMAN (71-489): 1.56e-78: 282: 24.20
+	Hs
		301134 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		KDM4B_HUMAN (86-464): 9e-76: 275: 22.72
+	Hs
		301146 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		KDM4B_HUMAN (86-464): 9e-76: 275: 22.72
+	Hs
		828320 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PHIP_HUMAN (425-1054): 9.63e-64: 240: 13.84
+	Hs
		600099 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		TAF1_HUMAN (382-1054): 4.35e-62: 235: 15.61
+	Hs
		828394 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		BRWD1_HUMAN (448-1085): 3.04e-61: 233: 14.10
+	Hs
		935038 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PHIP_HUMAN (425-1054): 9.63e-64: 240: 13.84
+	Hs
		600123 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		TAF1_HUMAN (382-1054): 4.35e-62: 235: 15.61
+	Hs
		828180 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		AF17_HUMAN (270-521): 3.76e-60: 227: 34.07
+	Hs
		876589 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		AF17_HUMAN (270-521): 3.76e-60: 227: 34.07
+	Hs
		299041 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PHF14_HUMAN (241-603): 4.93e-57: 216: 21.69
+	Hs
		828386 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		BRD7_HUMAN (574-748): 2.04e-56: 210: 32.77
+	Hs
		299045 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PHF14_HUMAN (241-603): 4.93e-57: 216: 21.69
+	Hs
		935266 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		BRD7_HUMAN (574-748): 2.04e-56: 210: 32.77
+	Hs
		256961 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		KDM4A_HUMAN (283-488): 9.15e-52: 201: 33.33