HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~MCM2_N
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 904 Hs			1 128
+	Hs
		469967 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		832655 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A1A_HUMAN (5-125): 2.64e-55: 170: 62.30
+	Hs
		832496 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40
+	Hs
		832567 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		832672 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A1J_HUMAN (5-125): 1.65e-54: 168: 62.30
+	Hs
		832683 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2AJ_HUMAN (5-128): 1.33e-54: 168: 60.80
+	Hs
		832648 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A1H_HUMAN (5-125): 4.19e-54: 167: 62.30
+	Hs
		391599 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		470300 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A1_HUMAN (5-125): 1.18e-53: 166: 62.30
+	Hs
		555351 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Hs
		594831 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A1D_HUMAN (5-125): 9.61e-54: 166: 63.12
+	Hs
		832523 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12
+	Hs
		832548 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A3_HUMAN (5-125): 8.16e-54: 166: 63.12
+	Hs
		832623 MCM2_HUMAN (1-904): 0: 1078: 100.00		H2A1C_HUMAN (5-125): 9.3e-54: 166: 62.30
+	Hs
		391569 MCM4_HUMAN (2-885): 0: 847: 28.42		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		555318 MCM4_HUMAN (2-885): 0: 847: 28.42		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Hs
		708464 MCM4_HUMAN (2-885): 0: 847: 28.42		H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12
+	Hs
		469956 MCM5_HUMAN (169-902): 0: 768: 29.43		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Sc
		667659 MCM2_YEAST (11-821): 0: 819: 46.70		H2AZ_YEAST (4-126): 3.22e-39: 129: 66.67
+	Hs
		391570 MCM5_HUMAN (169-902): 0: 768: 29.43		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30