HitPredict

Interactor 1: VIPR2 (P41587)
Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Helodermin-preferring VIP receptor) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (PACAP-R3) (VPAC2 receptor) (VPAC2R)
Gene: VIPR2

Interactor 2: CERS6 (Q6ZMG9)
Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291)
Gene: CERS6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 438 Hs			1 384
+	Hs
		835328 VIPR2_HUMAN (1-438): 4.12e-132: 389: 100.00		CERS5_HUMAN (6-375): 6.68e-154: 440: 64.96
+	Hs
		1042757 PTH1R_HUMAN (12-422): 4.25e-116: 353: 35.07		CERS6_HUMAN (1-384): 8.92e-163: 463: 100.00
+	Hs
		835360 VIPR2_HUMAN (1-438): 4.12e-132: 389: 100.00		CERS2_HUMAN (7-342): 1.14e-146: 422: 44.64
+	Hs
		880164 PTH2R_HUMAN (4-438): 3.52e-106: 327: 31.68		CERS6_HUMAN (1-384): 8.92e-163: 463: 100.00
+	Hs
		733046 VIPR1_HUMAN (12-438): 1.05e-120: 360: 46.05		CERS2_HUMAN (7-342): 1.14e-146: 422: 44.64
+	Hs
		867989 GLR_HUMAN (20-435): 1.58e-92: 289: 33.94		CERS5_HUMAN (6-375): 6.68e-154: 440: 64.96
+	Hs
		878043 AGRE5_HUMAN (64-424): 2.21e-80: 266: 18.28		CERS6_HUMAN (1-384): 8.92e-163: 463: 100.00
+	Hs
		1251726 AGRG2_HUMAN (66-419): 3.35e-77: 260: 16.10		CERS6_HUMAN (1-384): 8.92e-163: 463: 100.00