Protein: CERS5
Ceramide synthase 5 (CerS5) (LAG1 longevity assurance homolog 5) (Sphingoid base N-palmitoyltransferase CERS5) (EC 2.3.1.291) (Sphingosine N-acyltransferase CERS5) (EC 2.3.1.24)

Gene: CERS5
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q8N5B7

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005789 - endoplasmic reticulum membrane
GO:0014003 - oligodendrocyte development
GO:0030148 - sphingolipid biosynthetic process
GO:0046513 - ceramide biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1327503

P2Y12
P2Y purinoceptor 12

3

17

High-throughput

0.609

High

702805

5HT2C
5-hydroxytryptamine receptor 2C

3

13

High-throughput

0.604

High

1029614

CD83
CD83 antigen

1

0

High-throughput

0.578

High

1327496

CERS2
Ceramide synthase 2

1

7

High-throughput

0.575

High

669026

FPR2
N-formyl peptide receptor 2

2

20

High-throughput

0.574

High

835328

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

8

High-throughput

0.574

High

1159079

C3AR
C3a anaphylatoxin chemotactic receptor

2

20

High-throughput

0.574

High

1327505

IPPK
Inositol-pentakisphosphate 2-kinase

2

3

High-throughput

0.574

High

907032

CCR6
C-C chemokine receptor type 6

2

14

High-throughput

0.549

High

956940

CXCR4
C-X-C chemokine receptor type 4

2

16

High-throughput

0.549

High

1327509

NPTN
Neuroplastin

2

1

High-throughput

0.549

High

336552

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.536

High

1327497

BSCL2
Seipin

1

3

High-throughput

0.536

High

1327498

SEC62
Translocation protein SEC62

1

3

High-throughput

0.536

High

182658

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.489

High

711571

NK3R
Neuromedin-K receptor

1

4

High-throughput

0.489

High

867989

GLR
Glucagon receptor

1

10

High-throughput

0.489

High

1031113

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

1

High-throughput

0.489

High

1239005

NIPA3
Magnesium transporter NIPA3

1

3

High-throughput

0.489

High

1327492

MACOI
Macoilin

1

1

High-throughput

0.489

High

1327501

HCAR1
Hydroxycarboxylic acid receptor 1

1

16

High-throughput

0.489

High

1327504

TTYH1
Protein tweety homolog 1

1

3

High-throughput

0.489

High

1249016

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

1280335

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

1327494

LPAR1
Lysophosphatidic acid receptor 1

1

12

High-throughput

0.479

High

1327506

ZDH11
Palmitoyltransferase ZDHHC11

1

1

High-throughput

0.445

High

218456

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

704043

5HT1E
5-hydroxytryptamine receptor 1E

1

10

High-throughput

0.407

High

870264

S6A12
Sodium- and chloride-dependent betaine transporter

1

13

High-throughput

0.407

High

870382

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

13

High-throughput

0.407

High

886102

CXCR3
C-X-C chemokine receptor type 3

1

16

High-throughput

0.407

High

1101585

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

15

High-throughput

0.407

High

1211931

S35F1
Solute carrier family 35 member F1

1

9

High-throughput

0.407

High

1236220

MFSD5
Molybdate-anion transporter

1

3

High-throughput

0.407

High

1313755

S15A3
Solute carrier family 15 member 3

1

6

High-throughput

0.407

High

1327493

ZNT7
Zinc transporter 7

1

6

High-throughput

0.407

High

1327499

S1PR3
Sphingosine 1-phosphate receptor 3

1

13

High-throughput

0.407

High

1327502

S22A4
Solute carrier family 22 member 4

1

7

High-throughput

0.407

High

1327508

FZD10
Frizzled-10

1

3

High-throughput

0.407

High

1327495

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.279

Low

1135738

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1327500

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1327507

S23A1
Solute carrier family 23 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025