HitPredict

Interactor 1: BNI1 (P41832)
Protein BNI1 (Pointed projection formation protein 3) (Sensitive to high expression protein 5) (Synthetic lethal 39)
Gene: BNI1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.916

Property	Details
Experiments	39667500, 21880892, 24133141, 9082982, 22247555
Identification Methods	pull down, two hybrid, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~FH2
Common GO terms	GO:0005884 - actin filament GO:0030010 - establishment of cell polarity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1953 Sc			1 375
+	Hs
		953218 FHOD1_HUMAN (966-1921): 3.41e-103: 362: 14.13		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		993405 FHOD1_HUMAN (966-1921): 3.41e-103: 362: 14.13		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		1200992 FMNL3_HUMAN (179-726): 4.19e-69: 256: 13.23		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		953147 FMN2_HUMAN (1319-1782): 4.88e-89: 325: 16.94		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		993358 FMN2_HUMAN (1319-1782): 4.88e-89: 325: 16.94		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		995856 FMN2_HUMAN (1319-1782): 4.88e-89: 325: 16.94		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Sc
		824659 BNR1_YEAST (1316-1848): 4.64e-86: 313: 29.46		ACT_YEAST (1-375): 0: 594: 100.00
+	Dm
		386985 Q8SY43_DROME (992-1771): 7.58e-83: 302: 12.36		ACT2_DROME (2-375): 0: 594: 88.77
+	Sp
		534536 CDC12_SCHPO (37-958): 1.75e-80: 297: 14.90		ACT_SCHPO (1-375): 0: 591: 89.60
+	Hs
		993299 FMNL2_HUMAN (158-716): 1.29e-68: 255: 12.79		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		977747 FMNL3_HUMAN (179-726): 4.19e-69: 256: 13.23		ACTA_HUMAN (2-375): 0: 589: 86.63
+	Hs
		252430 DIAP1_HUMAN (222-805): 6.73e-63: 239: 13.61		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		953134 DIAP3_HUMAN (219-765): 2.56e-61: 233: 12.39		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		252442 DIAP1_HUMAN (222-805): 6.73e-63: 239: 13.61		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		953207 DAAM1_HUMAN (255-804): 2.66e-53: 207: 12.90		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		952859 INF2_HUMAN (349-686): 3.48e-17: 90.5: 12.43		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		993199 INF2_HUMAN (349-686): 3.48e-17: 90.5: 12.43		ACTG_HUMAN (1-375): 0: 599: 89.07
+	Hs
		995624 INF2_HUMAN (349-686): 3.48e-17: 90.5: 12.43		ACTC_HUMAN (2-375): 0: 591: 87.17