Interactor 1: MRE11 (P49959)
Double-strand break repair protein MRE11 (EC 3.1.-.-) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A)
Gene: MRE11
Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.993 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27173435, 23530059, 26215093, 11504724, 11062235, 8756642, 9705271, 34348893, 16982765, 22833675, 23912341, 12607003, 17500065, 16391231, 15734743, 26455393, 10783165, 28363998, 30179224, 28369484 and 16 others
more... |
| Identification Methods | affinity chromatography technology, biochemical, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA_23~Metallophos, Metallophos~SbcC_Walker_B, AAA_23~Mre11_DNA_bind |
| Common GO terms | GO:0000019 - regulation of mitotic recombination GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0000729 - DNA double-strand break processing GO:0000781 - chromosome, telomeric region and 21 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
