HitPredict

Interactor 1: EPS15 (P42567)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: EP15R (Q60902)
Epidermal growth factor receptor substrate 15-like 1 (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) (Eps15-related protein) (Eps15R)
Gene: Eps15l1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9446614
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0030132 - clathrin coat of coated pit
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 897 Mm			1 907
+	Hs
		839840 EPS15_HUMAN (1-897): 8.04e-154: 476: 88.65		EP15R_HUMAN (1-862): 1.35e-145: 454: 92.01
+	Hs
		839708 EPS15_HUMAN (1-897): 8.04e-154: 476: 88.65		EPS15_HUMAN (1-905): 3.33e-124: 399: 42.71
+	Mm
		839852 EPS15_MOUSE (1-897): 1.03e-143: 450: 100.00		EPS15_MOUSE (1-905): 2.2e-104: 346: 42.96
+	Hs
		839768 EPS15_HUMAN (1-897): 8.04e-154: 476: 88.65		ITSN1_HUMAN (2-522): 6.16e-37: 153: 13.24
+	Cl
		47464 A0A8I3PJA6_CANLF (1-897): 8.73e-150: 466: 88.69		F1PHV6_CANLF (2-522): 3.24e-36: 150: 12.86
+	Mm
		839864 EPS15_MOUSE (1-897): 1.03e-143: 450: 100.00		ITSN1_MOUSE (2-516): 7.16e-35: 146: 14.89
+	Hs
		64403 EPS15_HUMAN (1-897): 8.04e-154: 476: 88.65		A6H8W8_HUMAN (108-776): 1.75e-26: 119: 11.28
+	Hs
		839838 EPS15_HUMAN (1-897): 8.04e-154: 476: 88.65		ITSN2_HUMAN (108-768): 2.39e-23: 109: 10.70
+	Hs
		772658 EPS15_HUMAN (1-897): 8.04e-154: 476: 88.65		MYH9_HUMAN (383-781): 7.79e-15: 81.6: 7.38
+	Rn
		97303 ITSN1_RAT (3-853): 5.26e-80: 286: 15.49		E9PSY8_RAT (9-413): 2.71e-47: 184: 19.66
+	Hs
		1154186 EP15R_HUMAN (1-849): 2.98e-90: 307: 42.22		ITSN1_HUMAN (2-522): 6.16e-37: 153: 13.24
+	Hs
		64409 EP15R_HUMAN (1-849): 2.98e-90: 307: 42.22		A6H8W8_HUMAN (108-776): 1.75e-26: 119: 11.28
+	Hs
		1453438 EP15R_HUMAN (1-849): 2.98e-90: 307: 42.22		ITSN2_HUMAN (108-768): 2.39e-23: 109: 10.70
+	Mm
		1221960 EP15R_MOUSE (1-894): 2.44e-76: 269: 30.94		ITSN1_MOUSE (2-516): 7.16e-35: 146: 14.89
+	Hs
		1362024 CTTB2_HUMAN (275-846): 8.06e-41: 165: 15.55		CTTB2_HUMAN (419-906): 2.89e-35: 147: 12.93
+	Hs
		1217577 MRCKB_HUMAN (160-839): 9.15e-43: 171: 11.00		MRCKA_HUMAN (216-813): 5.6e-25: 114: 10.27