HitPredict

Interactor 1: EP15R (Q60902)
Epidermal growth factor receptor substrate 15-like 1 (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) (Eps15-related protein) (Eps15R)
Gene: Eps15l1

Interactor 2: ITSN1 (Q9Z0R4)
Intersectin-1 (EH and SH3 domains protein 1)
Gene: ITSN1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	10064583
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0048488 - synaptic vesicle endocytosis
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 907 Mm			1 1714
+	Hs
		1154186 EP15R_HUMAN (1-862): 1.35e-145: 454: 92.01		ITSN1_HUMAN (1-1714): 0: 872: 93.61
+	Hs
		839768 EPS15_HUMAN (1-905): 3.33e-124: 399: 42.71		ITSN1_HUMAN (1-1714): 0: 872: 93.61
+	Cl
		47464 A0A8I3PJA6_CANLF (1-905): 1.24e-115: 376: 43.09		F1PHV6_CANLF (1-1714): 0: 890: 93.14
+	Mm
		839864 EPS15_MOUSE (1-905): 2.2e-104: 346: 42.96		ITSN1_MOUSE (1-1714): 0: 889: 100.00
+	Hs
		1453438 EP15R_HUMAN (1-862): 1.35e-145: 454: 92.01		ITSN2_HUMAN (1-1713): 0: 716: 55.73
+	Hs
		64409 EP15R_HUMAN (1-862): 1.35e-145: 454: 92.01		A6H8W8_HUMAN (1-1713): 0: 716: 56.53
+	Hs
		64403 EPS15_HUMAN (1-905): 3.33e-124: 399: 42.71		A6H8W8_HUMAN (1-1713): 0: 716: 56.53
+	Hs
		839838 EPS15_HUMAN (1-905): 3.33e-124: 399: 42.71		ITSN2_HUMAN (1-1713): 0: 716: 55.73
+	Rn
		97303 E9PSY8_RAT (9-413): 2.71e-47: 184: 19.66		ITSN1_RAT (1-1714): 0: 876: 97.43
+	Hs
		1154087 ITSN1_HUMAN (2-522): 6.16e-37: 153: 13.24		ITSN1_HUMAN (1-1714): 0: 872: 93.61
+	Hs
		1154182 ITSN1_HUMAN (2-522): 6.16e-37: 153: 13.24		ITSN2_HUMAN (1-1713): 0: 716: 55.73
+	Hs
		539965 EPS15_HUMAN (1-905): 3.33e-124: 399: 42.71		BCR_HUMAN (722-1675): 1.53e-72: 269: 13.07
+	Hs
		839840 EP15R_HUMAN (1-862): 1.35e-145: 454: 92.01		EPS15_HUMAN (444-926): 1.3e-17: 91.6: 12.85
+	Mm
		839856 EP15R_MOUSE (1-907): 3.53e-141: 444: 100.00		EPS15_MOUSE (424-595): 2.26e-12: 74.3: 19.77
+	Hs
		839708 EPS15_HUMAN (1-905): 3.33e-124: 399: 42.71		EPS15_HUMAN (444-926): 1.3e-17: 91.6: 12.85
+	Hs
		1154138 ITSN1_HUMAN (2-522): 6.16e-37: 153: 13.24		PREX1_HUMAN (1183-1614): 1.14e-73: 275: 18.89
+	Mm
		839852 EPS15_MOUSE (1-905): 2.2e-104: 346: 42.96		EPS15_MOUSE (424-595): 2.26e-12: 74.3: 19.77